Ncert Exercises & Solutions

Q. 13. A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Defined your answer.

The statement is correct. Because of the degeneracy of codons, mutations at third base of codon usually does not result into any change is a phenotype. This is called silent mutations.

On other hands, if codon is change in a way that now it specifies another amino acid, it may other the protein function as it happens in case of

β

-globin of hemoglobin protein. Where a substitution of valine instead of glutamic acid causes change in its structure and function and resulting into a sickle-cell trait.

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