plays an important role in the transportation of oxygen. At the alveolus, the low and high favors the formation of hemoglobin. At the tissues, the high and low favor the dissociation of oxygen from oxyhemoglobin. Hence, the affinity of hemoglobin for oxygen is enhanced by the decrease of in blood. Therefore, oxygen is transported in the blood as oxyhemoglobin and oxygen dissociates from it at the tissues.