The salient features of the Double-helix structure of DNA include all the following except:
1. It is made of two polynucleotide chains, where the backbone is constituted by
sugar-phosphate, and the bases project inside.
2. The two chains have anti-parallel polarity.
3. The bases in two strands are paired through hydrogen bonds (H-bonds)
forming base pairs (bp).
4. The two chains are coiled in a left-handed fashion. 

Subtopic:  DNA Double Helix |
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There is now enough evidence to suggest that essential life processes (such as metabolism, translation, splicing, etc.), evolved around:
1. DNA
2. RNA
3. Proteins
4. Lipids
Subtopic:  DNA Fingerprinting |
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A transcription unit in DNA is defined primarily by the three regions in the DNA which include all the following except:
1. A promoter
2. An operator
3. Structural gene
4. A terminator
Subtopic:  Transcription |
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The earlier technique of DNA fingerprinting involved Southern blot and all the following except:
1. digestion of DNA by deoxyribonuclease
2. separation of DNA fragments by electrophoresis
3. hybridisation using labelled VNTR probe
4. detection of hybridised DNA fragments by autoradiography
Subtopic:  DNA Fingerprinting |
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Which histone is not a part of the octamer that forms the core of histone molecules in a nucleosome?
1. H1
2. H2A
3. H2B
3. H3
Subtopic:  DNA Packaging |
 76%
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Consider the two statements:
Assertion (A):   It is necessary to define the boundaries that would demarcate the region and the strand of DNA that would be transcribed.
Reason (R):  In transcription, only a segment of DNA and only one of the strands is copied into RNA.
 
1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are True but (R) is not the correct explanation of (A).
3. (A) is True but (R) is False.
4. Both (A) and (R) are False.
Subtopic:  Transcription |
 67%
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Consider the two statements:
Assertion (A):  When Griffith injected a mixture of heat-killed S and live R bacteria, the mice died.
Reason (R): Mice infected with the S strain (virulent) die from pneumonia infection but mice infected with the R strain do not develop pneumonia.
 
1. Both (A) and (R) are True and (R) is the correct explanation of (A).
2. Both (A) and (R) are True but (R) is not the correct explanation of (A).
3. (A) is True but (R) is False.
4. Both (A) and (R) are False.
Subtopic:  Search for Genetic Material |
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Regarding DNA replication:
I: It is semi-conservative.
II: It is semi-discontinuous.
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic:  DNA Replication |
 77%
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The RNA polymerase I does not transcribe:
1. 28S rRNA
2. 18S rRNA
3. 5.8S rRNA
4. 5S rRNA

Subtopic:  Transcription |
 81%
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The repressor of the lac operon is synthesised:
 
1. all the time
2. only when lactose is present
3. only when lactose is absent
4. only when glucose is present in high amount
Subtopic:  Gene Regulation: Lac Operon |
 69%
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