Read the following statements:
A. Variation at genetic level arises due to mutation. 
B. Technique of DNA fingerprinting was initially developed by Alec Jeffreys
1. Only (B) is correct 
2. Both (A) and (B) are correct 
3. Only (A) is correct 
4. Both (A) and (B) are incorrect

Subtopic:  DNA Fingerprinting |
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In DNA fingerprinting, detection of hybridised DNA fragments is possible by 
1. Electrophoresis
2. Botting 
3. Autoradiography
4. Centrifugation 
Subtopic:  DNA Fingerprinting |
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The nitrogenous base not present in DNA is
1. Adenine
2. Thymine
3. Cytosine
4. Uracil
 
Subtopic:  DNA vs RNA as Genetic Material |
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Amongst the following, which one has least number of nucleotides in its genome?
1. \(\phi \cdot \times 174 \) bacteriophage
2. E. coli
3. Human 
4. Lambda phage 
Subtopic:  The DNA |
 77%
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The double helix model for the structure of DNA proposed by Watson and Crick was based on 
1. Visible light spectrum analysis 
2. Chromatography
3. X-ray diffraction data 
4. Autoradiography 
Subtopic:  The DNA |
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In a nucleotide, a phosphate group is linked to ___(i)___ of a nucleoside through ___(ii)___
Select the correct option to fill in the blanks (i) and (ii)
1. (i) OH of 3'C              (ii) Hydrogen bond 
2. (i) OH of 5'C              (ii) Phosphoester linkage
3. (I) 3' - C,                    (ii) Peptide bond 
4. (i) OH of 5'C              (ii) Glycosidic linkage 
Subtopic:  The DNA |
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Select the incorrect statement regarding the salient features of the double-helix structure of DNA 
1. It is made of two polynucleotide chains 
2. The two chains have anti-parallel polarity
3. Guanine is bonded with thymine by three H-bonds 
4. The two chains are coiled in a right-handed fashion 
Subtopic:  DNA Double Helix |
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If there is a flow of information from RNA to DNA then this process will be named as 
1. Reverse transcription 
2. Translation 
3. Replication
4. Transformation 
Subtopic:  The DNA |
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A nucleosome is composed of 
1. Positively charged DNA and negatively charged histone octamer
2. A negatively charged H1 histone and positively charged DNA molecule
3. Negatively charged DNA and positively charged histone octamer 
4. Negatively charged lysines and positively charged arginine amino acids
Subtopic:  DNA Packaging |
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In the experiment conducted by Griffith when a mixture of heat killed S-strain and live R-strain of Pneumococcus bacteria was injected into a healthy mice, it developed pneumonia. This was due to 
1. Reactivation of S-strain bacteria 
2. Transformation of S-strain bacteria into R-strain bacteria 
3. Synthesis of polysaccharide coat around heat killed S-strain bacteria
4. Transformed R-strain bacteria
Subtopic:  Search for Genetic Material |
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