The double helix model for the structure of DNA proposed by Watson and Crick was based on 
1. Visible light spectrum analysis 
2. Chromatography
3. X-ray diffraction data 
4. Autoradiography 

Subtopic:  The DNA |
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In a nucleotide, a phosphate group is linked to ___(i)___ of a nucleoside through ___(ii)___
Select the correct option to fill in the blanks (i) and (ii)
1. (i) OH of 3'C              (ii) Hydrogen bond 
2. (i) OH of 5'C              (ii) Phosphoester linkage
3. (I) 3' - C,                    (ii) Peptide bond 
4. (i) OH of 5'C              (ii) Glycosidic linkage 
Subtopic:  The DNA |
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Select the incorrect statement regarding the salient features of the double-helix structure of DNA 
1. It is made of two polynucleotide chains 
2. The two chains have anti-parallel polarity
3. Guanine is bonded with thymine by three H-bonds 
4. The two chains are coiled in a right-handed fashion 
Subtopic:  DNA Double Helix |
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If there is a flow of information from RNA to DNA then this process will be named as 
1. Reverse transcription 
2. Translation 
3. Replication
4. Transformation 
Subtopic:  The DNA |
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A nucleosome is composed of 
1. Positively charged DNA and negatively charged histone octamer
2. A negatively charged H1 histone and positively charged DNA molecule
3. Negatively charged DNA and positively charged histone octamer 
4. Negatively charged lysines and positively charged arginine amino acids
Subtopic:  DNA Packaging |
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In the experiment conducted by Griffith when a mixture of heat killed S-strain and live R-strain of Pneumococcus bacteria was injected into a healthy mice, it developed pneumonia. This was due to 
1. Reactivation of S-strain bacteria 
2. Transformation of S-strain bacteria into R-strain bacteria 
3. Synthesis of polysaccharide coat around heat killed S-strain bacteria
4. Transformed R-strain bacteria
Subtopic:  Search for Genetic Material |
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A radioactive sulphur containing bacteriophage is allowed to attach to E. coli that contains radioactive phosphorus. The viruses produced in this bacteria by this infection will have 
1. Radioactive protein capsule and non-radioactive genetic material
2. Radioactive protein capsule and radioactive genetic material 
3. Non-radioactive protein capsule and radioactive genetic material 
4. Non-radioactive protein capsule and non-radioactive genetic material 
Subtopic:  Search for Genetic Material |
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The discontinuously synthesised fragments of DNA are joined by the enzyme 
1. DNA ligase
2. DNA-dependent DNA polymerase 
3. Phosphorylase
4. Topoisomerase
Subtopic:  DNA Replication |
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If E. coli completes the process of DNA replication within 38 minutes then the rate of polymerisation of DNA would be approximately
1. \(4.6 \times 10^6\) bp/second 
2. 500 bp/second 
3. 230 bp/second 
4. 2000 bp/second 
Subtopic:  DNA Replication |
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In a transcription unit, the promoter is located towards 
1. 5' end of the templates strand 
2. 5' end of the coding strand 
3. 3' end of the non-template strand 
4. 3' end of the sense strand 
Subtopic:  Transcription |
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