Consider the given two statements:
Assertion: Retroviruses are one known exception to the central dogma in molecular biology as proposed by Francis Crick.
Reason: In retroviruses a sequence of nucleotides is copied from an RNA template during the synthesis of a molecule of DNA.
 
1. Both Assertion and Reason are true but Reason does not correctly explain the Assertion.
2. Assertion is true but Reason is False.
3. Assertion is false but Reason is True.
4. Both Assertion and Reason are true and Reason correctly explains the Assertion.

Subtopic:  The DNA |
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Nucleosome:
I: is formed by the wrapping of negatively charged DNA around the negatively charged histone octamer.
II: typically contains 200 bp of DNA helix.
III: constitutes the repeating unit of a structure in nucleus called chromatin.
IV: is seen as ‘beads-on-string’ structure when viewed under electron microscope (EM).
1. Only I, II and III are correct
2. Only I, III and IV are correct
3. Only II, III and IV are correct
4. I, II, III and IV are correct
Subtopic:  DNA Packaging |
 84%
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Consider the given two statements:
Assertion (A): Euchromatin is said to be transcriptionally active chromatin, whereas heterochromatin is inactive.
Reason (R): Light stained region of chromatin is euchromatin and dark stained region is heterochromatin.
 
1. Both (A) and (R) are True but (R) does not correctly explain (A).
2. (A) is True but (R) is False.
3. (A) is False but (R) is True.
4. Both (A) and (R) are True and (R) correctly explains (A).
Subtopic:  The DNA |
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All the following can be logical conclusions of Griffith experiment except:
 
1. The R strain bacteria had somehow been transformed by the heat-killed S strain bacteria.
2. Some ‘transforming principle’, transferred from the heat-killed S strain, had enabled the R strain
to synthesise a smooth polysaccharide coat and become virulent.
3. The transformation must be due to the transfer of the genetic material.
4. The biochemical nature of genetic material must be the protein
Subtopic:  Search for Genetic Material: II |
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Regarding Hershey and Chase experiment:
Statement I: Bacteria that were infected with viruses that had radioactive proteins were not radioactive.
Statement II: Proteins did not enter the bacteria from the viruses.
 
1. Statement I is correct; Statement II is incorrect
2. Statement I is incorrect; Statement II is incorrect
3. Statement I is correct; Statement II is correct
4. Statement I is incorrect; Statement II is correct
Subtopic:  Search for Genetic Material: II |
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A molecule that can act as a genetic material should be able to generate its replica (Replication). Therefore:
I: Both the nucleic acids (DNA and RNA) can act as the genetic material.
II: Proteins cannot act as the genetic material.
 
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic:  DNA vs RNA as Genetic Material |
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Consider the given two statements:
Assertion (A): Viruses having RNA genome and having shorter life span mutate and evolve faster.
Reason (R): RNA being unstable, mutates at a faster rate.
 
1. Both (A) and (R) are True but (R) does not correctly explain (A).
2. (A) is True but (R) is False.
3. (A) is False but (R) is True.
4. Both (A) and (R) are True and (R) correctly explains (A).
Subtopic:  DNA vs RNA as Genetic Material |
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Matthew Meselson and Franklin Stahl , in1958, demonstrated that DNA replication produces two daughter DNA molecules each composed of:
1. two old strands
2. two new strands
3. one old and one new strand
4. two strands with variable proportion of new and old DNA
Subtopic:  Search for Genetic Material: II |
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Consider the given two statements:
Assertion: On one strand (the template with polarity 3'→5'), the replication is continuous, while on the other (the template with polarity 5'→3'), it is discontinuous.
Reason: The DNA-dependent DNA polymerases catalyse polymerisation only in one direction, that is 3'→5'.
 
1. Both Assertion and Reason are true but Reason does not correctly explain the Assertion.
2. Assertion is true but Reason is False.
3. Assertion is false but Reason is True.
4. Both Assertion and Reason are true and Reason correctly explains the Assertion.
Subtopic:  DNA Replication: II |
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While defining the two strands of the DNA in the structural gene of a transcription unit the coding strand is the one that:
1. has the polarity 3'→5'
2. has the sequence same as RNA (except uracil at the place of thymine)
3. is displaced during transcription
4. codes for the transcript formed
Subtopic:  Transcription:II |
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