The mature human RBCs are biconcave disc shaped. What is the advantage of such a shape?
1. It facilitates oxygen uptake and delivery.
2. It allows the cells to hold more hemoglobin.
3. It gives more room for the nucleus and organelles.
4. It keeps them from leaking out through the walls of capillaries.

When the red blood cells get near the end of their life span they:
1. are less likely to become damaged
2. become more fragile
3. are less likely to rupture
4. are less likely to be phagocytized in the spleen or liver

Identify the group in which the formed elements of the human blood are arranged in order of increasing size:
1. red blood cell, neutrophil, platelet
2. platelet, red blood cell, neutrophil
3. neutrophil, platelet, red blood cell
4. platelet, neutrophil, red blood cell

During the RBC cycling, all the following can occur except:
1. amino acids can be recycled into new proteins
2. the entire heme group is eliminated by the liver
3. iron is removed before heme is converted to bilirubin
4. liver dysfunction can cause accumulation of bilirubin in the body

A person has a complete blood count done. Which of the following would not be normal?
1. total RBC count - 5.0 million /µL
2. total WBC count – 1500 /µL
3. total platelet count - 225,000 /µL
4. hemoglobin – 14.5 g / 100 ml

Once released from the bone marrow into the circulation, the average life span of a red blood cell is about
1. 72 hours
2. one week
3. 4 months
4. 2 years

Platelet plug formation is initiated when platelets come into contact with
1. undamaged endothelial cells.
2. fibrinogen in the connective tissue beneath damaged blood vessels.
3. collagen fibers in the connective tissue beneath damaged blood vessels.
4. antithrombin.

An intravascular clot and its fragments are respectively called as:
1. hematoma; thrombosis
2. thrombus; hematoma
3. thrombus; embolus
4. embolus; thrombus

The cytoplasmic granules released by thrombocytes during platelet plug formation, which attract more platelets to the plug are:
1. prostacyclin and NO
2. erythropoietin and bilirubin
3. heparin and plasmin
4. ADP and thromboxanes

Coagulation of blood can be prevented by removal of which of the following in the blood?