The volume occupied by an atom is greater than the volume of the nucleus by a factor of about:
1. \(10\)
2. \(10^5\)
3. \(10^{10}\)
4. \(10^{15}\)

If \(M(A,~Z)\), \(M_p\)${}_{}$, and \(M_n\) denote the masses of the nucleus \(^{A}_{Z}X,\) proton, and neutron respectively in units of \(u\) \((1~u=931.5~\text{MeV/c}^2)\) and represent its binding energy \((BE)\) in \(\text{MeV}\). Then:

The energy equivalent of \(0.5\) g of a substance is:
1. \(4.5\times10^{13}\) J
2. \(1.5\times10^{13}\) J
3. \(0.5\times10^{13}\) J
4. \(4.5\times10^{16}\) J

The energy required in \(\text{MeV/c}^2 \) to separate \({ }_8^{16} \mathrm{O}\) into its constituents is:
(Given: mass defect for \({ }_8^{16} \mathrm{O}=0.13691~ \text{amu}\))