Mendelian disorders are mainly determined by:
1. | Alteration or mutation in a single gene. |
2. | Chromosomal gross structural changes. |
3. | Recombination between linked genes. |
4. | Jumping genes |
What is the mode of inheritance of phenylketonuria?
1. | Autosomal recessive | 2. | Autosomal dominant |
3. | Sex linked recessive | 4. | Sex linked dominant |
In cases of Phenylketonuria:
1. | The affected individual lacks an enzyme that converts the amino acid tyrosine into phenylalanine. |
2. | The affected individual makes an enzyme that converts the amino acid tyrosine into phenylalanine. |
3. | The affected individual makes an enzyme that converts the amino acid phenylalanine into tyrosine. |
4. | The affected individual lacks an enzyme that converts the amino acid phenylalanine into tyrosine. |
In Phenylketonuria,
I. | Phenylpyruvic acid and other derivatives are accumulated in the brain resulting in mental retardation. |
II. | These are also excreted through urine because of their poor absorption by the kidney. |
1. | Only I is correct | 2. | Only II is correct |
3. | Both are correct | 4. | Both are incorrect |