Regarding Mendelian disorders :
1. | Color blindness is more common in the females of the species. |
2. | Sickle cell anemia occurs due to the substitution of valine by glutamic acid in the globin chain of haemoglobin. |
3. | Individuals affected by phenylketonuria lack an enzyme that converts tyrosine to phenylalanine. |
4. | Thalassemia is inherited as an autosomal recessive trait. |