If there are 999 bases in RNA that code for a protein with 333 amino acids, and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?
1. | 1 | 2. | 11 |
3. | 33 | 4. | 333 |
Identifying all the genes in the genome that are transcribed into RNA is called:
1. | Expressed Sequence Tag | 2. | Sequence Annotation |
3. | Inverse PCR | 4. | Retrotransposition |
For the multiplication of any alien piece of DNA in an organism it needs to be a part of a chromosome that has a specific:
1. | Telomeric sequence | 2. | Multiple cloning site |
3. | Ori | 4. | Selectable marker |
Griffith co-injected the heat-killed S and live R strains of Pneumococcus bacterium into the mice and much to his surprise the mice developed pneumonia and died. He concluded that:
I: | Live R was transformed into Live S strain as he was able to isolate Live S strain from the blood of the infected mice. |
II: | Bacterial transformation is a stable and heritable change as the culture of bacteria isolated from dead mice was unable to infect other mice. |
1. | Both I and II are correct |
2. | Only I is correct |
3. | Only II is correct |
4. | Both I and II are incorrect |
The radius of the double helix of B-DNA [Watson and Crick model] is approximately:
1. | 1.0 nm | 2. | 2.0 nm |
3. | 0.34 nm | 4. | 3.4 nm |
An RNA primer is essential for DNA synthesis carried out by DNA polymerase III. This is because, to synthesize DNA, DNA polymerase III requires:
1. | A free 3’ – PO4 group |
2. | A free 5’ – PO4 group |
3. | A free 3’ – OH group |
4. | A free 5’ – OH group |
Which of the following possible modes of replication was eliminated by Meselson and Stahl based on the finding after one generation of replication of the bacterium?
1. | Dispersive | 2. | Semi-conservative |
3. | Conservative | 4. | Both 1 and 3 |
In eukaryotes, RNA polymerase III transcribes:
1. | hnRNA, snRNAs and 5.8S RNA |
2. | tRNA, 5.8S RNA and snRNAs |
3. | tRNA, 5SrRNA and snRNAs |
4. | rRNAs – 28S, 18S and 5S |
Identify the incorrect statement:
1. | The DNA of the bacteriophage ϕ X 174 has 5386 nucleotides. |
2. | Bacteriophage lambda DNA has 48502 base pairs. |
3. | The DNA of Escherichia coli has 4.6 X 103 base pairs. |
4. | Haploid content of human DNA is 3.3 X 109 base pairs. |
In a DNA strand, two nucleotides are linked through a ___________ linkage to form a dinucleotide.
1. 3’ – 5’ phosphodiester bond
2. 5’ – 3’ phosphodiester bond
3. 1’ N-glycosidic bond
4. Two or three hydrogen bonds