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Q. No.

Which of the following pairs of codons encode the same amino acid?

1.AUG and AUC2.UAA and UAC
3.GUA and GUG4.UAG and UAC

Subtopic:  Translation |
 59%
Level 3: 35%-60%
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Griffith wanted to make a vaccine to prevent pneumonia. He injected heat-killed S-strain bacteria into the mice for this purpose. How can a killed bacteria help in making a vaccine?

1. The heat-killed bacteria is a more potent toxin than the live one.
2. Protein denaturation due to heat changes the proteins of the bacterium.
3. Molecules from the cell surface are still intact and can provoke an immune response.
4. DNA molecules can transform other strains of bacteria.
Subtopic:  Search for Genetic Material |
 57%
Level 3: 35%-60%
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Griffith's experiment discovered bacterial transformation which in his experiment means:

1. A mutation in the R strain made them virulent.
2. A mutation in the S strain made them non-virulent.
3. A rough strain passed genetic information to a smooth strain.
4. A smooth strain passed genetic information to a rough strain.
Subtopic:  Search for Genetic Material |
 79%
Level 2: 60%+
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Avery, MacLeod, and McCarty used DNase in their experiment because:

1. It enabled them to isolate pure DNA samples.
2. It enabled them to isolate pure protein samples.
3. This allowed them to demonstrate that removing the DNA prevents transformation.
4. It made sure that RNA will always be present when they attempted to transform the R strain.
Subtopic:  Search for Genetic Material |
 85%
Level 1: 80%+
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What key observation regarding Garrod'sinborn of metabolism leads to a landmark discovery in molecular biology?

1. Identification of a defective gene in individuals with alkaptonuria.
2. Identification of a defective gene in parents of alkaptonuria patients.
3. Identification of a defective enzyme in individuals with alkaptonuria.
4. Identification of the inheritance pattern of alkaptonuria as autosomal recessive.
Subtopic:  Search for Genetic Material |
Level 3: 35%-60%
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T2 bacteriophage was used by Hershey and Chase to conclusively prove that DNA and not protein is the genetic material because:

1. It makes capsomeres with the help of its genes.
2. It injects its genetic material into a bacterial cell.
3. It can undergo either the lytic or lysogenic life cycle
4. It enters the bacterial cell to cause infection.
Subtopic:  Search for Genetic Material |
 73%
Level 2: 60%+
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Identify the correct statements regarding a replisome:

I: It is a complex of several proteins.
II: It includes enzymes like DNA polymerase, DNA helicase, and primase.
III: It is found at the replication fork during DNA synthesis.
 
1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  DNA Replication |
 73%
Level 2: 60%+
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The origin of replication is a particular sequence in a genome at which replication is initiated. This region is AT-rich because:

1. DnaA proteins bind to AT-rich sites.
2. DnaC proteins bind to AT-rich sites.
3. AT base pairs are more easily separated than GC base pairs.
4. AT base pairs contain more hydrogen bonds than GC base pairs.

Subtopic:  DNA Replication |
 77%
Level 2: 60%+
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What would be the actual inducer for the lac operon?

1.lactose2.allolactose
3.ß-galactosidase4.galactose

Subtopic:  Gene Regulation: Lac Operon |
Level 3: 35%-60%
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The primary RNA transcript in eukaryotes contains introns. This can be demonstrated by:

I: A comparison of the DNA and mRNA sequences.
II: A comparison of the genomic DNA and cDNA sequences.
III: A hybridization between DNA and mRNA molecules.
 
1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  Transcription: I |
 54%
Level 3: 35%-60%
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