The first clinical gene therapy was done for the treatment of:
1. | AIDS |
2. | Cancer |
3. | Cystic fibrosis |
4. | SCID (Severe Combined Immuno Deficiency) resulting from deficiency of ADA |
Why does Bt toxin not kill Bacillus thuringiensis?
1. | The bacillus keeps proteins in inclusions |
2. | The toxin exists in the bacillus as a pro-toxin |
3. | The bacillus protects its genetic material by methylation |
4. | The bacillus has a tough cell wall of peptidoglycan |
Cotton plants can be protected from corn borer by the proteins coded by:
1. | cryIAc | 2. | cryIIAb |
3. | cryIAb | 4. | cryIAd |
How were nematode-specific genes introduced in tobacco plants?
1. | Using page DNA | 2. | Using a retrovirus |
3. | By gene gun | 4. | Using Agrobacterium tumefaciens |
The first recombinant therapeutic product approved for human use was:
1. | Humulin | 2. | hGH |
3. | Factor VIII clotting factor | 4. | Erythropoietin |
ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA
Recombinant therapeutic [used for treatment] products are available for all the following disorders except:
1. | Hemophilia A | 2. | Pituitary dwarfism |
3. | Diabetes insipidus | 4. | Anemia due to renal failure |
Electroporation is:
1. | the process of separating charged molecules through a gel maintained in an electric field |
2. | the process of combining foreign DNA to an electrically charged vector molecule |
3. | the process of introducing DNA into cells by the application of high-voltage pulses |
4. | the process of protoplast fusion by the application of high-voltage pulses |
A direct target for gene therapy would include all the following cells except:
1. | erythrocytes | 2. | muscle fibers |
3. | hepatocytes | 4. | vascular endothelium |
Which of the following is a recombinant protein?
1. | Beta Galactosidase in E.coli | 2. | Insulin in humans |
3. | Somatotropin in humans | 4. | Interferon in E. coli |