Match each item in Column I with one item in Column II and chose your answer from the codes given below.
|
Column I |
Column II |
|
I. RNAi II. Ribozyme III. PCR IV. Monoclonal antibodies |
1. Fire and Mello 2. Thomas Cech 3. Kyle Mullis 4. Millstein and Kohler |
Codes:
| I | II | III | IV | |
| 1. | 1 | 2 | 3 | 4 |
| 2. | 2 | 1 | 4 | 3 |
| 3. | 2 | 1 | 3 | 4 |
| 4. | 1 | 2 | 4 | 3 |
Consider the following statements:
| I: | RNAi takes place in all eukaryotic organisms as a method of cellular defense. |
| II: | It involves the silencing of a specific mRNA due to complementary dsDNA molecules that prevent the translation of mRNA. |
| III: | Fire and Mello got the Nobel Prize for the discovery of RNAi. |
Which of the above statements are true?
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
RNAi is a mechanism to silence genes with the help of :
| 1. | ssRNA | 2. | dsRNA |
| 3. | ssDNA | 4. | dsDNA |
A biological process in which RNA molecules inhibit gene expression or translation, by neutralizing targeted mRNA molecules is known as:
| 1. | Bioprospecting | 2. | Molecular pharming |
| 3. | RNA interference | 4. | Insertional mutagenesis |
Fire and Mello shared noble prize for RNAi while working on:
| 1. | Arabidopsis thaliana | 2. | Drosophila melanogaster |
| 3. | Coenorhabditis elegans | 4. | Zea mays |
| I: | involves silencing of a specific mRNA due to a complementary dsRNA molecule that binds to and prevents translation of the mRNA (silencing). |
| II: | has been used to create transgenic tobacco plants resistant to nematode Meloidogyne incognita |