Choose the correct option regarding Retrovirus:
1. | An RNA virus that synthesises DNA during infection |
2. | A DNA virus that synthesises RNA during infection |
3. | A ssDNA virus |
4. | A dsRNA virus |
Match each item in Column I with one item in Column II and chose your answer from the codes given below.
Column I |
Column II |
I. RNAi II. Ribozyme III. PCR IV. Monoclonal antibodies |
1. Fire and Mello 2. Thomas Cech 3. Kyle Mullis 4. Millstein and Kohler |
Codes:
I | II | III | IV | |
1. | 1 | 2 | 3 | 4 |
2. | 2 | 1 | 4 | 3 |
3. | 2 | 1 | 3 | 4 |
4. | 1 | 2 | 4 | 3 |
Pathophysiology is the:
1. Study of physiology of pathogen
2. Study of normal physiology of the host
3. Study of altered physiology of the host
4. None of the above
The first recombinant therapeutic product approved for human use was:
1. | Humulin | 2. | hGH |
3. | Factor VIII clotting factor | 4. | Erythropoietin |
A fragment of nucleic acid (DNA or RNA) that can be used to identify, usually through autoradiography, specific DNA or RNA molecules bearing the complementary sequence is called:
1. | Vector | 2. | Probe |
3. | Selectable marker | 4. | Reporter gene |
ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA
A hybridization probe used in molecular diagnosis is commonly tagged with a radioactive isotope to allow for its visualization. A common such radioactive isotope that can be used is:
1. | 60Co | 2. | 32P |
3. | 15N | 4. | 131I |
1. | Only I | 2. | Only II |
3. | Both I and II | 4. | Neither I nor II |