Select the option which is not correct with respect to enzyme action:
1. Substrate binds with enzyme at its active site.
2. Addition of a lot of succinate does not reverse the inhibition of succinic dehydrogenase by malonate.
3. A non-competitive inhibitor binds the enzyme at a site distinct from that which binds the substrate.
4. Malonate is a competitive inhibitor of succinic dehydrogenase.

All the following are examples of competitive enzyme inhibition except:
1. Sulfa drugs used as antibacterial agents
2. Ethyl alcohol used in methyl alcohol poisoning
3. Malonate inhibiting succinic dehydrogenase enzyme
4. Glucose 6 phosphate inhibiting hexokinase in brain