Q. No. The most useful classification of drugs for medicinal chemistry is based on:
1. The basis of chemical structure.
2. The basis of drug action.
3. The basis of molecular targets.
4. The basis of the pharmacological effect.
A molecule that cannot act as a target for drug function in the body is:
1. Carbohydrates
2. Lipids
3. Vitamins
4. Proteins
Drugs can be classified on the basis of:
1. Pharmacological effect.
2. Chemical structure.
3. Molecular targets.
4. All of the above.
The incorrect statement among the following regarding enzyme inhibitors is:
| 1. | They inhibit the catalytic activity of the enzyme. |
| 2. | They prevent the binding of substrate. |
| 3. | Generally, a strong covalent bond is formed between an inhibitor and an enzyme. |
| 4. | Inhibitors can be competitive or non-competitive. |
Select the correct option based on statements below:
| Assertion (A): | Competitive inhibitors compete with the natural substrate for their attachment to the active sites of enzymes. |
| Reason (R): | In competitive inhibition, the inhibitor binds to the allosteric site of the enzyme. |
| 1. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 2. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 3. | Both (A) and (R) are false. |
| 4. | (A) is true but (R) is false. |
1. Diphenylhydramine
2. Norethindrone
3. Omeprazole
4. Chloramphenicol
Match the class of compounds given in Column I with their functions given in Column II.
| Column I | Column II |
| A. Antagonists | 1. Communicate messages between two neurons and that between neurons to muscles. |
| B. Agonists | 2. Bind to the receptor site and inhibit its natural function. |
| C. Chemical messenger | 3. Crucial to the body's communication process. |
| D. Receptors | 4. Mimic is the natural messenger. |
Codes
| A | B | C | D | |
| 1. | 2 | 4 | 1 | 3 |
| 2. | 3 | 1 | 4 | 2 |
| 3. | 1 | 4 | 3 | 2 |
| 4. | 4 | 3 | 2 | 1 |
A better substitute of Mg(OH)2 as medicine is-
1. Ranitidine
2. Histamine
3. Cyclopam
4. Ipranzoid
A compound among the following that can be used as a tranquilizer is:
1. Promethazine
2. Valium
3. Naproxen
4. Mifepristone
The molecule among the following that is an antidepressant is:
1. Chloroxylenol
2. Bithional
3. Cocaine
4. Penicillin-G
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