Name the enzyme that facilitates opening of DNA helix during transcription.
1. DNA helicase
2. DNA polymerase
3. RNA polymerase
4. DNA ligase
If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is bp, then the length of the DNA is approximately:
1. | 2.5 meters | 2. | 2.2 meters |
3. | 2.7 meters | 4. | 2.0 meters |
Which of the following statements is correct?
1. Adenine pairs with thymine through one H-bond.
2. Adenine pairs with thymine through three H-bonds.
3. Adenine does not pair with thymine.
4. Adenine pairs with thymine through two H-bonds.
Choose the correct pair from the following :
1. | Polymerases | - | Break the DNA into fragments |
2. | Nucleases | - | Separate the two strands of DNA |
3. | Exonucleases | - | Make cuts at specific positions within DNA |
4. | Ligases | - | Join the two DNA molecules |
The first phase of translation is:
1. Recognition of DNA molecule
2. Aminoacylation of tRNA
3. Recognition of an anti-codon
4. Binding of mRNA to ribosome
The term 'Nuclein' for the genetic material was used by :
1. Franklin
2. Meischer
3. Chargaff
4. Mendel
In the polynucleotide chain of DNA, a nitrogenous base is linked to the –OH of:
1. | 2'C pentose sugar | 2. | 3'C pentose sugar |
3. | 5'C pentose sugar | 4. | 1'C pentose sugar |
E.coli has only 4.6 × base pairs and completes the process of replication within 18 minutes, then the average rate of polymerization is approximately:
1. | 2000 base pairs/second | 2. | 3000 base pairs/second |
3. | 4000 base pairs/second | 4. | 1000 base pairs/second |
Which is the basis of genetic mapping of the human genome as well as DNA fingerprinting?
1. Polymorphism in the DNA sequence
2. Single nucleotide polymorphism
3. Polymorphism in the hnRNA sequence
4. Polymorphism in the RNA sequence
What initiation and termination factors are involved in transcription in prokaryotes?
1. , respectively
2. , respectively
3. , respectively
4. , respectively