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Q. No.Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA?
1. Rosalind Franklin
2. Maurice Wilkins
3. Erwin Chargaff
4. Meselson and Stahl
Subtopic: DNA Double Helix |
74%
Level 2: 60%+
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DNA is a polymer of nucleotides which are linked to each other by 3’-5’ phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
1. Replace purine with pyrimidines
2. Remove/Replace 3' OH group in deoxy ribose
3. Remove/Replace 2' OH group with some other group in deoxy ribose
4. Both ‘b’ and ‘c’
1. Replace purine with pyrimidines
2. Remove/Replace 3' OH group in deoxy ribose
3. Remove/Replace 2' OH group with some other group in deoxy ribose
4. Both ‘b’ and ‘c’
Subtopic: DNA Double Helix |
55%
Level 3: 35%-60%
Hints
Discontinuous synthesis of DNA occurs in one strand, because:
| 1. | DNA molecule being synthesised is very long |
| 2. | DNA dependent DNA polymerase catalyses polymerisation only in one direction (5’ → 3’) |
| 3. | it is a more efficient process |
| 4. | DNA ligase joins the short stretches of DNA |
Subtopic: DNA Replication |
90%
Level 1: 80%+
Hints
Which of the following steps in transcription is catalysed by RNA polymerase?
1. Initiation
1. Elongation
3. Termination
4. All of the above
1. Initiation
1. Elongation
3. Termination
4. All of the above
Subtopic: Transcription |
Level 3: 35%-60%
Hints
Control of gene expression in prokaryotes take place at the level of:
1. DNA-replication
2. Transcription
3. Translation
4. None of the above
1. DNA-replication
2. Transcription
3. Translation
4. None of the above
Subtopic: Gene Regulation: Introduction |
72%
Level 2: 60%+
Hints
Which of the following statements is correct about the role of regulatory proteins in transcription in prokaryotes?
1. They only increase expression
2. They only decrease expression
3. They interact with RNA polymerase but do not affect the expression
4. They can act both as activators and as repressors
1. They only increase expression
2. They only decrease expression
3. They interact with RNA polymerase but do not affect the expression
4. They can act both as activators and as repressors
Subtopic: Gene Regulation: Introduction |
65%
Level 2: 60%+
Hints
Which was the last human chromosome to be completely sequenced:
1. Chromosome 1
2. Chromosome 11
3. Chromosome 21
4. Chromosome X
1. Chromosome 1
2. Chromosome 11
3. Chromosome 21
4. Chromosome X
Subtopic: Human Genome Project |
83%
Level 1: 80%+
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Which of the following are the functions of RNA?
1. It is a carrier of genetic information from DNA to ribosomes synthesising polypeptides.
2. It carries amino acids to ribosomes.
3. It is a constituent component of ribosomes.
4. All of the above.
1. It is a carrier of genetic information from DNA to ribosomes synthesising polypeptides.
2. It carries amino acids to ribosomes.
3. It is a constituent component of ribosomes.
4. All of the above.
Subtopic: Translation |
93%
Level 1: 80%+
Hints
While analysing the DNA of an organism a total number of 5386 nucleotides were found out of which the proportion of different bases were: Adenine = 29%, Guanine = 17%, Cytosine = 32%, Thymine = 17%. Considering the Chargaff’s rule it can be concluded that:
1. it is a double stranded circular DNA
2. It is single stranded DNA
3. It is a double stranded linear DNA
4. No conclusion can be drawn
1. it is a double stranded circular DNA
2. It is single stranded DNA
3. It is a double stranded linear DNA
4. No conclusion can be drawn
Subtopic: DNA Double Helix |
57%
Level 3: 35%-60%
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In some viruses, DNA is synthesised by using RNA as template. Such a DNA is called:
1. A-DNA
2. B-DNA
3. cDNA
4. rDNA
1. A-DNA
2. B-DNA
3. cDNA
4. rDNA
Subtopic: The DNA |
54%
Level 3: 35%-60%
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