The viruses generally used for gene therapy are:
1. | ds DNA virus | 2. | ss DNA virus |
3. | Reovirus | 4. | Reterovirus |
Bacillus thuringiensis (Bt) strains have been used to design novel:
1. | Biofertilizers | 2. | Biometallurgic techniques |
3. | Biomineralization processes | 4. | Bioinsecticidal plants |
1. | A part of mature insulin molecule |
2. | Responsible for formation of disulphide bridges |
3. | Removed during maturation of pro-insulin to insulin |
4. | Responsible for its biological activity |
A probe which is a molecule used to locate homologous sequences in a mixture of DNA or RNA molecules could be:
1. | A ssRNA | 2. | A ssDNA |
3. | Either RNA or DNA | 4. | Can be ssDNA but not ssRNA |
A protoxin is:
1. | A primitive toxin | 2. | A denatured toxin |
3. | Toxin produced by protozoa | 4. | Inactive toxin |
The trigger for activation of toxin of Bacillus thuringiensis is:
1. | Acidic pH of stomach |
2. | High temperature |
3. | Alkaline pH of gut |
4. | Mechanical action in the insect gut |
Silencing of a gene could be achieved through the use of:
1. | RNAi only | 2. | antisense RNA only |
3. | both RNAi and antisense RNA | 4. | none of the above |
RNAi, as a mechanism of cellular defense, takes place in:
1. | All bacteria | 2. | All unicellular organisms |
3. | All plants only | 4. | All eukaryotic organisms |
The first clinical gene therapy trial was given in 1990 to a 4 year girl with:
1. | Alpha – 1 antitrypsin deficiency |
2. | Cystic fibrosis |
3. | Adenosine deaminase deficiency |
4. | Chronic myeloid leukemia |
Over 95 % of all transgenic animals are:
1. | Mice | 2. | Pigs |
3. | Sheep | 4. | Rabbits |