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Basic amino acids have more amino groups than carboxylic groups. Which of the following set has both basic amino acids?
1. Glutamic acid and Glycine 
2. Histidine and Lysine
3. Arginine and Valine 
4. None of these

Palmitic acid and stearic acid are
1. Saturated fatty acids so essential for the body
2. Saturated F. acids so non-essential for the body
3. Unsaturated F acids so essential for the body
4. Unsaturated F acids so non-essential for the body

Which of the following classes of biomolecules are known to have catalytic properties?
1. Protein and lipid 
2. Protein and RNA
3. Protein and Carbohydrate 
4. Carbonhydrate and lipid

About 93% of cellular material is composed of three elements which are
1. Carbon, Nitrogen & Hydrogen 
2. Carbon, Oxygten & Hydrogen
3. Carbon, Nitrogen & oxygen 
4. Oxygen, Hydrogen & Calcium

In quaternary configuration of protein, disulphide bondmay form between following amino acids
1. Methionine and serine 
2. Tyrosine and valine
3. Methionine and crysteine 
4. Proline and cysteine

Starch, cellulose and glycogen are all carbohydrates. The property which they all share is
1. Branched structure 
2. $\mathrm{\alpha }$ - 1, 4 linkage
3. Polymers of glucose 
4. Originate from plant sources

In structure the keratin of mammalian hairs is
1. $\mathrm{\alpha }$ - helical like silk fibroin 
2. $\mathrm{\beta }$ - pleated like silk
3. $\mathrm{\alpha }$ - helical unlike silk fibroin 
4. $\mathrm{\beta }$ - pleated unlike silk

Which of the following statement is true?
1. Cellulose and Glycogen both have $\mathrm{\beta }$-glucose
2. Glycogen has $\mathrm{\alpha }$-glucose and Cellulose has $\mathrm{\beta }$-glucose
3. Glycogen and Cellulose both have $\mathrm{\alpha }$-glucose
4. Cellulose has $\mathrm{\alpha }$-glucose and Glycogen has $\mathrm{\beta }$-glucose

Which of the following is only a ribose nucleotide?
1. Cytosine-pentose sugar-phosphate 
2. Guanine-pentose sugar-phosphate
3. Thymine-pentose sugar-phosphate 
4. Uracil-pentose sugar-phosphate

Which of the following sequence is correct on the basis of increasing molecular weight?
1. DNA, ATP, NADP, AMP 
2. AMP, ATP, NADP, DNA
3. ATP, AMP, DNA, NADP 
4. ATP, ADP, NADP, DNA

Cellulose the most important constituent of plant cell is made up of:
1. Unbranched chain of glucose molecules linked by $\mathrm{\beta }$-(1 $\to$4) glycosidic linkage
2. Branched chain of glucose molecules linked by $\mathrm{\alpha }$-(1$\to$4)-glycosidic bonds at the site of branching
3. Branched chain of glucose molecules linked by $\mathrm{\alpha }$-(1$\to$4)-glycosidic bond at the site of branching
4. Branched chain of glucose molecules linked by $\mathrm{\alpha }$-(1$\to$4)-glycosidic bond in straight chain and b-(1$\to$6) glycosidic bond at the site of branching.

According to induced fit theory of Koshland
1. Fine geometrical alternations of enzyme protein occur during formation of E-S complex
2. Substrate undergoes fine geometrical alternations while active site of enzyme remains unchanged
3. Active sites are static like a key
4. None of these

In an experiment to study fermentation by yeast, temperature was increased from 20°C to 30°C, rate of enzyme catalysed reaction increases by
1. 2 times 
2. 5 times
3. 10 times 
4. No effect

Cyanide is a metabolic poison as it:
1. Inhibits the enzymes of TCA cycle
2. Inhibits the enzymes cytochrome oxidase and blocks tissue respiration
3. Inhibits glycolysis
4. Stops protein synthesis

Which of the following statement is not true for allosteric inhibition?
1. Inhibitor has no structural similarity with the substrate
2. It is irreversible
3. Inhibitor attaches to an area other than active site
4. Conformation of enzymes is changed

In case of Michaelis – Menten’s equation, if substrate concentration is much higher than Km, rate of enzyme activity is
1. V_max/2 
2. V_max
3. Zero 
4. Between zero and V_max/2

Which of the following graph represents non-competitive inhibition?

Which statement about protein is correct
1. Quaternary structure of protein primary amino acid sequence
2. In protein only right handed helices are observed.
3. In protein tertiary structure is the result of the interaction of two or more independent polypeptide chain
4. Protein primary structure is altered by the interaction of the polypeptide chain with co-factors required for enzyme activity such as metal ions or vitamins.

Which of the following statement is not corrected about quaternary structure of protein?
1. it always contains more than one polypeptide chain.
2. polypeptide chains are present in right handed helix.
3. intra and inter molecular hydrogen bond stabilize the structure of proteins.
4. Hemoglobin is an example of quaternary structure of protein

The graph indicates that binding of haemoglobin with oxygen is

1. Competitive
2. Non-competitive
3. Allosteric
4. Uncompetitive

Which of the following statement is not correct about triglycerides?
1. It contains both saturated and unsaturated fatty acids
2. Higher the proportion of saturated fatty acids in triglycerides more likely they are to be liquid at a given temperature
3. They do not form hydrogen bonds with water molecules and therefore do not dissolve in water.
4. It is the commonest lipid in nature and are further classified as fats or oils

Tropocollagen is characterized by the presence of
1. Great tensile-strength
2. Three polypeptide chains are wound around each other
3. The three strands of chain are held together by hydrogen bonds
4. All of these

Ezymes are divided ito 6 classes each with 4 – 13 subclasses and named accordingly by a four-digits number. Enzyme which catalyses hydrolysis of ester, ether, and P-N, bonds, its first digit will be assigned as
1. 1 . a . b. c 
2. 2 . a . b . c
3. 3 . a . b . c 
4. 4 . a . b . c

Which of the following is incorrect statement?
1. All the elements present in a sample of earth’s crust are also present in a sample of living tissue.
2. All the carbon compounds that we get from living tissues can be called as biomolecules
3. Inorganic compounds like sulphate and phosphate are seen in acid insoluble fraction
4. The relative abundance of carbon and hydrogen with respect to other elements is higher in any living organism than in earth’s crust

Which of the following structure will lead to the formation of zwitterions?

Purines are 9 membered double ring nitrogenous bases which posses nitrogen at
1. 1, 3, 6, 9 position 
2. 2, 3, 7, 8 position
3. 1, 3, 7, 9 position 
4. 5, 6, 7, 8 position

Which of the following is incorrect with respect to Chargaff rule?
1. Purines and pyrimidines occur in equal amount
2. Base ratio $\frac{\mathrm{A}+\mathrm{G}}{\mathrm{C}+\mathrm{T}}$ is specific for a species
3. Molar amount of adenine is equal to that of thymine and cytosine equal to guanine
4. Phosphate and deoxyribose sugar occur in equal amount

Given below is a graphical representation of concept of activation energy. Choose the correct set for the labeled portion A, B, C and D in the graph

1. A – Potential energy
    B – Substrate
    C – Transition state,
    D – Product
2.  A – Substrate
     B – Potential energy
     C – Transition state,
      D – Product
3.  A – Substrate
     B – Transition state,
     C – Product
     D – Potential energy
4.  A – Potential energy
     B – Transition state
     C – Substrate
     D – Product

The enzymes that catalyse removal of groups from substrates by mechanisms other than hydrolysis leaving double bonds belong to
1. Oxidoreductase 
2. Isomerases
3. Ligases 
4. Lyases

The mechanism of enzyme inhibition used in the control of bacterial pathogens is
1. Competitive inhibition 
2. Non-competitive inhibition
3. Feed back inhibition 
4. Allosteric inhibition