Hargobind Khorana was awarded the noble prize for:
1. discovering DNA
2. discovering RNA
3. discovering DNA polymerase
4. chemical synthesis of a gene
The transfer RNA molecule in 3D appears
1. L-shaped
2. E-shaped
3. V-shaped
4. S-shaped
Length of one turn of the helix in a B-form DNA is approximately
1. 3.4 nm
2. 2 nm
3. 0.34 nm
4. 20 nm
A mutation at a gene locus changes a character due to change in
1. DNA replication
2. Protein synthesis pattern
3. RNA transcription pattern
4. Protein structure
Production of human protein in bacterial genetic engineering is possible because
1. Human chromosome replicate bacterial cell
2. Mechanism of gene regulation is identical in humans and bacteria
3. Bacterial cell can undertake RNA splicing
4. Genetic code is universal
Using reverse transcriptase or gene synthesis has an advantage over the shotgun approach in obtaining a copy of the gene required as:
1. | the gene produced can easily be ligated to the vector |
2. | the gene produced is not a split gene |
3. | the gene produced does not require a promoter to be expressed |
4. | the gene produced does not require an ori to replicate |
What will be the sequence of mRNA produced by the following stretch of DNA?
3' ATGCATGCATGCATG 5' TEMPLATE STRAND
5' TACGTACGTACGTAC 3' CODING STRAND
1. 3' AUGCAUGCAUGCAUG 5'
2. 5' UACGUACGUACGUAC 3'
3. 3' UACGUACGUACGUAC 5'
4. 5' AUGCAUGCAUGCAUG 3'
Match the following RNA polymerases with their transcribed products:
Column-I |
Column-II |
||
(a) |
RNA polymerase I |
(i) |
tRNA |
(b) |
RNA polymerase II |
(ii) |
rRNA |
(c) |
RNA polymerase III |
(iii) |
hnRNA |
Select the correct option from the following:
Options: | (a) | (b) | (c) |
1. | i | iii | ii |
2. | i | ii | iii |
3. | ii | iii | i |
4. | iii | ii | i |
From the following, identify the correct combination of salient features of the Genetic Code:
1. | Universal, Non-ambiguous, Overlapping |
2. | Degenerate, Overlapping, Commaless |
3. | Universal, Ambiguous, Degenerate |
4. | Degenerate, Non-overlapping, Non-ambiguous |
Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage?
1. Beadle and Tatum
2. Messelson and Stahl
3. Hershey and Chase
4. Jacob and Monod