In eukaryotes, RNA polymerase III transcribes:

1. hnRNA, snRNAs and 5.8S RNA
2. tRNA, 5.8S RNA and snRNAs
3. tRNA, 5SrRNA and snRNAs
4. rRNAs – 28S, 18S and 5S

Subtopic:  Transcription: I |
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Identify the incorrect statement:

1. The DNA of the bacteriophage  ϕ X 174 has 5386 nucleotides.
2. Bacteriophage lambda DNA has 48502 base pairs.
3. The DNA of Escherichia coli has 4.6 X 103 base pairs.
4. Haploid content of human DNA is 3.3 X 109 base pairs.
Subtopic:  The DNA |
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In a DNA strand, two nucleotides are linked through a ___________ linkage to form a dinucleotide.

1. 3’ – 5’ phosphodiester bond

2. 5’ – 3’ phosphodiester bond

3. 1’ N-glycosidic bond

4. Two or three hydrogen bonds

Subtopic:  DNA Double Helix |
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The bacterial promotor sequence usually found at the -10 position (ten base pairs upstream of the transcription start site) is:
1. TTGACA
2. TAGACA
3. TATAAT
4. TATTAT

Subtopic:  Transcription: I |
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Replication in prokaryotes differs from replication in eukaryotes for which of the following reasons?

1.  Prokaryotic chromosomes have histones, whereas eukaryotic chromosomes do not.
2.  Prokaryotic chromosomes have a single origin of replication, whereas eukaryotic chromosomes have many.
3.  The rate of elongation during DNA replication is slower in prokaryotes than in eukaryotes.
4.  Prokaryotes produce Okazaki fragments during DNA replication, but eukaryotes do not.

Subtopic:  DNA Replication: I |
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Consider the following two statements:

I: During transcription, the template strand is read in a 3'-to-5' direction.
II: During transcription, an RNA is transcribed in the 5'-to-3' direction.

The correct statements is/are:

1. I only 2. II Only
3. I and II 4. None
Subtopic:  Transcription: I |
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Identify the correct statements from the given statements and choose the correct option:

I: Both prokaryotic and eukaryotic mRNAs have a 5' cap.
II: Only prokaryotic mRNAs are polyadenylated at the 3' end.
III: In prokaryotes, transcription is coupled to translation.
IV: In eukaryotes, RNA splicing occurs after the mRNA is transported into the cytoplasm.
V: RNA splicing requires the formation of a spliceosome.
VI: Both prokaryotic and eukaryotic mRNAs are synthesized by RNA polymerase.

1. III, V, and VI only
2. II, III, V, and VI only
3. I, III, V, and VI only
4. I, III, IV, V, and VI only
Subtopic:  Transcription: I | Translation | Translation Mechanism |
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A molecule that can act as a genetic material must fulfill all the following criteria except:

1. It should be able to generate its replica.

2. It should chemically and structurally be stable.

3. It should be able to express itself in the form of Medelian characters.
4. It should provide scope for rapid changes required for evolution.

Subtopic:  Search for Genetic Material |
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Histones are rich in:

1. Basic amino acids lysine and arginine

2. Acidic amino acids lysine and arginine

3. Basic amino acids glutamate and aspartate

4. Acidic amino acids glutamate and aspartate

Subtopic:  DNA Packaging |
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On examining a sample of human DNA, it was found that it contains approximately 24 % thymine. Which of the following would be true based on this finding?

1. The amount of adenine in a similar sample of DNA from any human being will be approximately 24 %.

2. The amount of adenine in a similar sample of DNA from any living being will be approximately 24 %.

3. The amount of adenine in a similar sample of DNA from any eukaryotic cell will be approximately 24 %.

4. The amount of adenine in a similar sample of DNA from any mammal will be approximately 24 %.

Subtopic:  Search for Genetic Material:I | Search for Genetic Material: II |
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