If Meselson and Stahl's experiment is continued for four generations in bacteria, the ratio of N15/N15: N15/N14: N14/N14 containing DNA in the fourth generation would be:

1. 1:1:0 2. 1:4:0
3. 0:1:3 4. 0:1:7

Subtopic:  Search for Genetic Material:I | Search for Genetic Material: II |
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If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is:

5' -ATGAATG-3',

the sequence of bases in its RNA transcript would be;

1. 5'-AUGAAUG-3'

2. 5'-UACUUAC-3'

3. 5'-CAUUCAU-3'

4. 5'-GUAAGUA-3'

Subtopic:  Transcription: I | Transcription:II |
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The RNA polymerase holoenzyme transcribes:

1. the promoter, structural gene and the terminator region

2. the promoter and the terminator region

3. the structural gene and the terminator region

4. the structural gene only.

Subtopic:  Transcription: III |
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If the base sequence of a codon in mRNA is 5'-AUG-3', the sequence of tRNA pairing with it must be:

1. 5'-UAC-3'

2. 5'-CAU-3'

3. 5'-AUG-3'

4. 5'-GUA-3'

Subtopic:  Translation | Translation Mechanism |
From NCERT
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The amino acid attaches to the tRNA at its:

1. 5' - end

2. 3' - end

3. Anti codon site

4. DHU loop

Subtopic:  Translation | Translation Mechanism |
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To initiate translation, the mRNA first binds to:

1. The smaller ribosomal sub-unit,

2. The larger ribosomal sub-unit

3. The whole ribosome

4. No such specificity exists.

Subtopic:  Translation | Translation Mechanism |
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In E.coli, the lac operon gets switched on when:

1. lactose is present and it binds to the repressor

2. repressor binds to operator

3. RNA polymerase binds to the operator

4. lactose is present and it binds to RNA polymerase

Subtopic:  Gene Regulation: Lac Operon |
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Identify the incorrect statement regarding the comparison of an RNA and a DNA molecule:

1. Both are composed of nucleotides joined by phosphodiester bonds.
2. Both have secondary and tertiary structures.
3. RNA is always single-stranded while DNA is always double-stranded.
4. Both have the same purine bases.
Subtopic:  DNA vs RNA as Genetic Material |
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Griffith wanted to make a vaccine to prevent pneumonia. He injected heat-killed S-strain bacteria into the mice for this purpose. How can a killed bacteria help in making a vaccine?

1. The heat-killed bacteria is a more potent toxin than the live one.
2. Protein denaturation due to heat changes the proteins of the bacterium.
3. Molecules from the cell surface are still intact and can provoke an immune response.
4. DNA molecules can transform other strains of bacteria.
Subtopic:  Search for Genetic Material |
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The functions of the telomeres include:

I: They prevent chromosomes from fusing with each other.
II: They prevent chromosomes from shrinking due to DNA loss during replication.
III: They allow chromosomes to segregate properly during cell division.

1. I and II only
2. I and III only
3. II and III only
4. I, II, and III
Subtopic:  The DNA |
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