Match the disorder in Column I with the location of the gene causing it in Column II and select the correct option from the codes given:

 

COLUMN I

 

COLUMN II

A.

Sickle cell anaemia

a.

Chromosome 11

B.

Phenylketonuria

b.

Chromosome 12

C.

Cystic fibrosis

c.

Chromosome 7

D.

Huntington’s disease

d.

Chromosome 4

Codes:

A B C D
1. a b c d
2. b a c d
3. a b d c
4. b a d c

Subtopic:  Mendelian Disorders |
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The pedigree shows the inheritance of red-green color blindness in a family. If II 3 marries a color-blind man, what is the probability that her first child will be normal?

1. ¼ 2. ½
3. 2/3 4. ¾
Subtopic:  Pedigree Analysis: Problem Solving |

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The blood groups possible in progeny of a type A mother and a type AB father can be
1. A, B, AB, and O
2. A, B, and AB
3. A and AB
4. A only

Subtopic:  Dominance Deviation from Mendel: 2 |
 75%
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The pedigree shown below cannot be:

I. Autosomal dominant disorder
II. Autosomal recessive disorder
III. Sex-linked dominant disorder
IV. Sex-linked recessive disorder
V. Holandric disorder
 
1. I, II, and III only 2. I, II, III, and V only
3. I, III, IV, and V only 4. I, II, III, IV and V
Subtopic:  Pedigree Analysis: Basics |

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The recombination frequencies for four different linked genes of Drosophila are shown in the figure:

 

The order of the four genes will be:

1.rb-cn-vg-b2.vg-b-rb-cn
3.cn-rb-b-vg4.b-rb-cn-vg

Subtopic:  Recombination & Gene Mapping |
 56%

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In a fruit fly, the eye colour trait is located on X-chromosome and the vestigial wing trait is located on an autosome. What is the possibility that a cross between a white-eyed male fruit fly with vestigial wings and a wild-type female who is heterozygous for both traits will result in a female offspring with vestigial wings and white eyes?

1. 1/16 2. 1/8
3. ¼ 4. ½
Subtopic:  Chromosomal Basis of Inheritance: Further Considerations |

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A dihybrid test cross results in a 1.2% frequency of recombination. This implies that:
1. genes are located on sex chromosomes.
2. genes are located on heterologous chromosomes.
3. genes exhibit epistatic two factor interaction.
4. genes are located very close to one another on the same chromosome.

Subtopic:  Recombination & Gene Mapping |
 79%

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In heterozygous condition, the dominant allele is able to express itself only in one sex. This is a
1. A sex limited trait
2. A sex influenced trait
3. A sex linked trait
4. sex-determining trait.

Subtopic:  Sex Linked Inheritance: Characteristics |

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Given below are different levels of organization of genetic material. Arrange them in the correct descending order of their size:

1. Genome, chromosome, gene, nucleotide
2. Gene, chromosome, nucleotide, genome
3. Chromosome, gene, genome, nucleotide
4. Chromosome, genome, nucleotide, gene
Subtopic:  Chromosomal Basis of Inheritance: Introduction |
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Which field of genetics is the oldest?
1. Transmission genetics.
2. Molecular genetics.
3. Population genetics.
4. Developmental genetics.

Subtopic:  Introduction to Genetics: 2 |

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