Q. No.Match each item in COLUMN I [genetic disorder] with its description in Column II and select the correct answer from the codes given:
COLUMN I
COLUMN II
A.
Huntington's disease
a.
Inability to metabolize certain lipids, affecting proper brain development and death in early childhood.
B.
Tay-Sachs disease
b.
Caused by a dominant single gene defect and generally does not appear until the individual is 35-45 years of age
C.
phenylketonuria
c.
Effects of this recessive disorder can be completely overcome by regulating the diet of the affected individual
D.
Cystic fibrosis
d.
This results from a defect in membrane proteins that normally function in chloride ion transport
Codes:
A B C D
1. a b c d
2. b a c d
3. a b d c
4. b a d c
COLUMN I
COLUMN II
A.
Huntington's disease
a.
Inability to metabolize certain lipids, affecting proper brain development and death in early childhood.
B.
Tay-Sachs disease
b.
Caused by a dominant single gene defect and generally does not appear until the individual is 35-45 years of age
C.
phenylketonuria
c.
Effects of this recessive disorder can be completely overcome by regulating the diet of the affected individual
D.
Cystic fibrosis
d.
This results from a defect in membrane proteins that normally function in chloride ion transport
A B C D
1. a b c d
2. b a c d
3. a b d c
4. b a d c
Genetics, an important branch of biology, is best defined as:
| 1. | The study of the transmission of traits from parent to offspring. |
| 2. | The study of genes and traits defined by genes. |
| 3. | The study of DNA. |
| 4. | The study of variation between members of a species. |
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In a dihybrid cross, AaBb x AaBb, the fraction of the offspring that will be homozygous for both traits is:
| 1. | 1/16 | 2. | 1/8 |
| 3. | 3/16 | 4. | ¼ |
In the pedigree shown, mating between individuals III 2 and III 3 results in a progeny, which is an affected female. Based on this information, most likely this disorder is:
| 1. | Holandric | 2. | Sex-linked dominant |
| 3. | Sex-linked recessive | 4. | Either 1 or 2 |
A dominant unit factor (trait) is best defined as
1. The most common trait in the population.
2. The trait that is seen in a heterozygous organism (hybrid).
3. A trait that reappears in the F2 of a monohybrid cross.
4. A trait that causes differential reproduction
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Mendel was able to propose laws of genetics mainly because:
| 1. | He knew about the correct sequence of DNA. |
| 2. | Mendel carefully established true breeding lines and used them in hybridization experiments carried out over multiple generations. |
| 3. | Mendel's use of peas as a model organism and his experience with plant breeding in his father's orchard. |
| 4. | He had analyzed the results of experiments of a large number of scientists before him. |
DNA mainly
1. stores information for protein synthesis.
2. mutates and leads to evolution
3. directs protein synthesis.
4. provides energy for the cell.
Black coat colour is a dominant trait while the albino trait is recessive in mice. You want to raise only black-coat mice as they appear more graceful to you. You crossed black mice with albino mice thinking that all progeny will be black based on dominance. You felt disappointed when your cross yielded only three black-coat mice out of seven. This is because you incorrectly:
| 1. | assumed that black alleles were more common than white. |
| 2. | assumed that white alleles were more common than black. |
| 3. | assumed that my black mouse was true-breeding. |
| 4. | assumed that my white mouse was true-breeding. |
Consider crossing over does not take place between chromosomes shown as:
(i) Chromosome 1: ABC/abc
(ii) Chromosome 2:Qr, qr.
Which of the following gametes will not be formed by this organism?
| 1. | ABCqr | 2. | abcqr |
| 3. | ABcqr | 4. | abcQr |
What would be the correct definition of a ‘locus’ in genetics ?
| 1. | One version of a gene. |
| 2. | The location of a gene along the chromosome. |
| 3. | The character of the gene effects. |
| 4. | The mechanism of action of a gene. |
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