A genome will be best defined as:
1. All the information in plasmids of a bacterium.
2. A homologous pair of chromosomes.
3. The complete DNA sequences in a diploid zygote.
4. All the DNA contained in a human gamete.
When DNA is replicated the first nucleotides are added by:
1. DNA primase
2. DNA polymerase III
3. DNA polymerase II
4. DNA ligase
A deoxyribonucleotide contains:
I: | Nitrogenous base. |
II: | Deoxyribose sugar. |
III: | Phosphate group. |
1. | Only I and II | 2. | Only I and III |
3. | Only II and III | 4. | I, II and III |
Constitutive heterochromatin includes:
1. The Barr body.
2. A region of active gene expression.
3. Telomeres.
4. Both 1 and 2.
What key observation regarding Garrod'sinborn of metabolism leads to a landmark discovery in molecular biology?
1. | Identification of a defective gene in individuals with alkaptonuria. |
2. | Identification of a defective gene in parents of alkaptonuria patients. |
3. | Identification of a defective enzyme in individuals with alkaptonuria. |
4. | Identification of the inheritance pattern of alkaptonuria as autosomal recessive. |
Proof reading, the error-correcting processes, first proposed by John Hopfield and Jacques Ninio, during DNA replication takes place by:
1. Endonuclease cleavage.
2. Exonuclease cleavage.
3. Methylation.
4. An induced-fit phenomenon.
Identify the incorrect statement regarding structure of DNA:
1. Pitch is 3.4nm and 10 base pairs.
2. The two strands are antiparallel.
3. Each pair of nucleotides is held together by three hydrogen bonds.
4. The diameter of the molecule is a uniform 2nm.
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T2 bacteriophage was used by Hershey and Chase to conclusively prove that DNA and not protein is the genetic material because:
1. | It makes capsomeres with the help of its genes. |
2. | It injects its genetic material into a bacterial cell. |
3. | It can undergo either the lytic or lysogenic life cycle |
4. | It enters the bacterial cell to cause infection. |
Chromatin is:
1. | Complete genetic sequences contained by members of a particular species. |
2. | The DNA-protein complex comprising of eukaryotic chromosomes. |
3. | Tandem repetitive sequences in the non-coding DNA. |
4. | All the transcription units in the genome. |
The nitrogenous bases purines and pyrimidines basically differ in that:
1. | The former is found in RNA while the latter is found in DNA. |
2. | The latter is found in RNA while the former is found in DNA. |
3. | The former contains a double-ring backbone, while the latter contains a single-ring backbone. |
4. | The latter contains a double-ring backbone while the former contains a single-ring backbone. |