For the first time, the synthesis of two DNA sequences of insulin was carried out by Eli Lilly in
(1) 1972
(2) 1981
(3) 1983
(4) 1987
Insulin chains produced by Eli Lilly using recombinant DNA technology, actually taken which of the following strain of bacteria?
(1) Escherichia coli
(2) Bacillus subtilis
(3) Saccharomyces cerevisiae
(4) Bacillus xenus
Gene therapy is not
(1) An attempt to correct a gene defect
(2) By which genes are inserted into an individual or embryo to take over the function of and compensate the non-functional gene.
(3) Genes are inserted into a person's cells and tissues to treat a disease
(4) Correction of environmental defect by inserting a gene
Which of the following is not correct about the first clinical gene therapy?
(1) 1990 year
(2) 5 year old kid
(3) Adenosine deamide deficiency
(4) Both B and C
The ADA deficiency is because of
(1) Substitution
(2) Inversion
(3) Deletion
(4) Insertion
The possible treatments of ADA deficiency are
(1) Bone Marrow Transplantation
(2) Enzyme replacement Therapy
(3) Both
(4) None of these
Which of the following therapies for ADA deficiency are not completely curative?
(1) Bone Marrow Transplantation
(2) Enzyme replacement Therapy
(3) Both A and B
(4) Both are completely curative
The first step of gene therapy would be
(1) Culture of the lymphocytes from patient's blood
(2) Using vector for transmitting gene
(3) cDNA was prepared
(4) cDNA was inserted directly into the cells
The last step of gene therapy would be
(1) The corrected lymphocytes are returned to the patients
(2) Culture of lymphocytes of the patient
(3) Introduction of correct gene in cultured cells
(4) Removal of corrected lymphocytes from culture
The permanent cure of gene therapy can be
(1) Cells isolated from bone marrow in an adult were cultured and transformed with corrected gene
(2) Cells isolated from thymus in an adult were cultured and transformed with corrected gene
(3) Cells isolated from bone marrow in an embryo were cultured and transformed with corrected gene
(4) Genes isolated from bone marrow were introduced into the cells at early embryonic stage