A permanent cure for ADA deficiency could be:

1.	Enzyme replacement therapy
2.	Bone marrow transplant
3.	Introduction of a functional ADA cDNA into lymphocytes
4.	Introduction of gene isolated from marrow cells producing ADA into early embryonic cells

Polymerase Chain Reaction is not used in :

1. Confirming presence of a pathogen during early infection

2. Identifying the mutated genes in suspected cancer patients

3. Isolating the gene of interest from host DNA to be cloned by recombinant procedures

4. Detection of the presence of HIV in suspected AIDS patient

If gene isolate from marrow cells producing ADA is introduced into cells at early embryonic stage, it could be a permanant cure of ADA deficiency because the early embryonic cells :

1. Are more differentiated than the later stage cells

2. Are constantly dividing and do not get differentiated 

3. Are easy to manipulate than the later stage cells

4. Are virtually immortal 

To test the safety of polio vaccine, the organisms used are transgenic :

1. Mice

2. Pigs

3. Monkey 

4. Cattle

If the goal were to create a plant resistant to an insecticide, which cell-based plant technology would be most effective ?

(1) clonal propagation

(2) cybridization

(3) protoplast fusion

(4) mutant selection

Which protein has been produced generating a transgenic sheep that is used for replacement therapy for individuals at risk from emphysema?
1. Plasminogen activator (rPA)
2. α-antitrypsin (ATT)
3. Casein
4. Amyloid precursor proteins

Consider the following statements :

I. The BCG vaccine is given as a protection against Tuberculosis

II. Oral polio vaccine is being used in the Pulse Polio Immunization programme in India

III. Hepatitis B vaccine is made with the help of recombinant E.Coli

Which of the above statements are true ?

1. I and II only

2. I and III only

3. II and III only

4. I,II and III

A genetically engineered micro-organism used successfully in bioremediation of oil spills is a species of:

(1) Pseudomonas

(2) Trichoderma

(3) Xanthomonas

(4) Bacillus

Which kind of therapy was given in 1990 to a four-year-old girl with Adenosine Deaminase (ADA) deficiency?

(1) Gene therapy 

(2) Chemotherapy

(3) Immunotherapy

(4) Radiation therapy

The two polypeptides of human insulin are linked together by

(1) phosphodiester bonds

(2) covalent bonds

(3) disulphide bridges

(4) hydrogen bonds