In DNA replication, the Okazaki fragments on the lagging strand are joined together by:

1. DNA ligase

2. DNA polymerase

3. Primase

4. Helicase 

The enzyme that catalyzes the peptide bonding in prokaryotes is located in the:

1. Leader region of the mRNA

2. Central part of tRNA

3. Smaller subunit of the ribosome

4. Larger subunit of the ribosome

In general, bacterial genes are regulated at the time of:

1. Transcription

2. Post transcription

3. Translation

4. Post translation  

The insertion or deletion of a base pair into the genetic code will cause a frame shift mutation unless the number of base pairs inserted or deleted is:

(1) One

(2) Two

(3) three

(4) Ten

Consider the following statements:

I. The largest known human gene is dystrophin at 2.4 million bases

II. Repeated sequences make up very large portion of the human genome

III. There are about 2.4 million locations where single base DNA differences occur in humans

Which of the above statements are true?

1. I and II only

2. I and III only

3. II and III only

4. I, II and III

Consider the following statements:

I. RNA is the genetic material of the QB bacteriophage

II. DNA chemically is less reactive and more stable than RNA

III. Viruses having RNA genome and having shorter life span mutate & evolve slowly.

Which of the above statements are true?

1. I and II only

2. I and III only

3. II and III only

4. I, II and III

Consider the following statements:

I. Inheritance of a character is affected by promoter and regulatory sequences of a structural gene.
II. The split-gene arrangement represents an ancient feature of the genome.

III. The process of splicing represents the dominance of RNA world.

which of the above statements are true?

1. I and II only

2. I and III only

3. II and III only

4. I, II and III

Consider the following statements:

I. All the reference point while defining a transcription unit is made with coding strand

II. It is the presence of a promoter in a transcription unit that also defines the template and coding strands

III. Exons are said to be sequences that do not appear in mature or processed RNA

Which of the above statements are true?

1. I and II only

2. I and III only

3. II and III only

4. I, II and III

Consider the following statements:

I. Deoxyribonucleoside triphosphates act as substrates as well as provide energy for polymerization reaction during DNA replication.

II. The replication of DNA is both semiconsenvative and semi- discontinuous

III. In bacterial DNA replication there are multiple ori and replication fork moves bi-directionally

Which of the above statements are true?

1. I and II only

2. I and III only

3. II and III only

4. I, II and III

Match each item in Column I with one item in Column II and chose your answer from the codes given below:

Codes

             I           II         III         IV

(1)         1           2           3           4

(2)         2           1           4           3

(3)         2           1           3           4

(4)         1           2           4           3