In DNA replication, the Okazaki fragments on the lagging strand are joined together by:

1. DNA ligase

2. DNA polymerase

3. Primase

4. Helicase 

The enzyme that catalyzes the peptide bonding in prokaryotes is located in the:

1. Leader region of the mRNA

2. Central part of tRNA

3. Smaller subunit of the ribosome

4. Larger subunit of the ribosome

In general, bacterial genes are regulated at the time of:

1. Transcription

2. Post transcription

3. Translation

4. Post translation  

The insertion or deletion of a base pair into the genetic code will cause a frame shift mutation unless the number of base pairs inserted or deleted is:

(1) One

(2) Two

(3) three

(4) Ten

If there are 999 bases in an RNA that codes for a protein with 333 amino acids and the base at position 901 is deleted such that the length of teh RNA becomes 998 bases, how many codons will be altered?

(1) 1

(2) 11

(3) 33

(4) 333

DNA fragments are

(1) positively charged

(2) negatively charged

(3) neutral

(4) either positively or negatively charged depending on their size

During DNA replication, Okazaki fragments are used to elongate

(1) The leading strand towards replication fork

(2) The lagging strand towards replication fork

(3) The leading strand away from replication fork

(2) The lagging strand away from replication fork

Spliceosomes are not found in cells of 

(1) plants

(2) fungi

(3) animals 

(4) bacteria

The final proof for DNA as the genetic material come from the experiments of 

1. Griffith

2. Hershey and chase 

3. Avery, Macleod and McCarty 

4.  Hargobind Khorana 

The association of histone H₁ with a nucleosome indicates 

(1) transcription is occuring

(2) DNA replication is occuring

(3) the DNA is condensed into chromatin fibre

(4) the DNA double helix is exposed