Which of the following can permanently cure ADA deficiency?
1. Bone marrow transplant
2. Enzyme replacement therapy
3. Introduction of the gene isolated from marrow cells producing ADA at early embryonic stages.
4. Introduction of a functional ADA cDNA (using a retroviral vector) into peripheral lymphocytes.

Subtopic:  Gene Therapy |
 91%
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Identify the incorrect statement regarding transgenic animals:
1. α-1 antitrypsin is being produced in a transgenic sheep
2. The first transgenic cow, Rosie, produced human protein-enriched milk (2.4 grams per litre).
3. Transgenic mice are being used to test the safety of the polio vaccine.
4. Over 95 percent of all existing transgenic animals are cattle.
Subtopic:  Transgenic Microbes & Animals |
 83%
From NCERT
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GEAC stands for:
1. Genetic Engineering Approval Committee  
2. Green Environment Action Committee
3. Genetic Engineering Appraisal Council
4. Genetic Ethics Approval Committee
Subtopic:  Ethical Issues |
 89%
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The term used to refer to the use of bio-resources by multinational companies and other organisations without proper authorisation from the countries and people concerned without compensatory payment is:
1. Bioprospecting
2. Biopiracy
3. Biomagnification
4. Bioaccumulation

Subtopic:  Ethical Issues |
 95%
From NCERT
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Identify the incorrectly matched pair:
1. Golden rice Vitamin B12 enriched rice
2. Rosie First transgenic cow
3. Bt Cotton Genetically modified pest resistant plant cotton variety
4. Basmati controversy Biopiracy
Subtopic:  Other GM Crops |
 83%
From NCERT
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A chronic respiratory disorder, commonly caused by cigarette smoking but rarely due to deficiency of α-1 antitrypsin enzyme, is:
1. Bronchial asthma 2. Tuberculosis
3. Emphysema 4. Pneumoconiosis
Subtopic:  Transgenic Microbes & Animals |
 94%
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ds RNA can be used during which one of the following ?
1. Gene sequencing
2. Polymerase Chain Reaction
3. Gene silencing
4. Autoradiography

Subtopic:  Interference RNA Tech |
 82%
From NCERT
NEET - 2022
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In gene therapy of Adenosine Deaminase (ADA) deficiency, the patient requires periodic infusion of genetically engineered lymphocytes because: 
1. Genetically engineered lymphocytes are not immortal cells.
2. Retroviral vector is introduced into these lymphocytes.
3. Gene isolated from marrow cells producing ADA is introduced into cells at embryonic stages 
4. Lymphocytes from patient's blood are grown in culture, outside the body.
Subtopic:  Gene Therapy |
 76%
From NCERT
NEET - 2022
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Statements related to human Insulin are given below.
Which statement(s) is/are correct about genetically engineered Insulin?
(a) Pro-hormone insulin contain extra stretch of C-peptide
(b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them.
(c) Insulin used for treating Diabetes was extracted from Cattles and Pigs.
(d) Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone.
(e) Some patients develop allergic reactions to the foreign insulin.
Choose the most appropriate answer from the options given below:
1. (c), (d) and (e) only
2. (a), (b) and (d) only
3. (b) only
4. (c) and (d) only
Subtopic:  Med Applications & Humulin |
From NCERT
NEET - 2022
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Genetically engineered insulin for human is produced from:
1. Escherichia coli
2. Psuedomonas putida
3. Bacillus thuringiensis
4. Rhizobium meliloti

Subtopic:  Med Applications & Humulin |
 94%
From NCERT
NEET - 2022
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