Frameshift mutation occurs when

(1) base is substituted

(2) base is deleted or added

(3) anticodons are absent

(4) none of these

Wobble hypothesis was given by

(1) R.W. Holley

(2) M. Nirenberg

(3) H.G. Khorana

(4) F.H.C. Crick

Which one of the following pairs of terms / names mean one and the same thing?

(1) Gene pool - genome

(2) Codon – gene

(3) Cistron – triplet

(4) DNA fingerprinting - DNA profiling

What is true about tRNA?

(1) It binds with an amino acid at it 3’ end

(2) It has five double stranded regions

(3) It has a codon at one end which recognizes the anticodon on messenger RNA

(4) It looks like clover leaf in the three dimensional structure.

Which one of the following correctly represents the manner of replication of DNA?

(1)

(2)

(3)

(4)

Which one of the following codons codes for the same information as UGC?

(1) UGU

(2) UGA

(3) UAG

(4) UGG

The total number of nitrogenous bases in human genome is estimated to be about

1. 3.5 million

2. 35 thousand

3. 35 million

4. 3.1 billion

What is the first step in the Southern Blot technique?

(1) Denaturation of DNA on the gel for hybridization with specific probe

(2) Production of a group of genetically identical cells

(3) Digestion of DNA by restriction enzyme

(4) Isolation of DNA from a nucleated cell such as the one from the scene of crime

Given below is a representation of a kind of chromosomal mutation. What is the kind of mutation represented?

(1) Deletion

(2) Duplication

(3) Inversion

(4) Reciprocal translocation

Which one of the following pairs is correctly matched with regard to the codon and the amino acid coded by it?

(1) UUA - valine

(2) AAA - lysine

(3) AUG - cysteine

(4) CCC - alanine