Which of the following statements is false?

I.	Insulin was originally extracted from pancreas of slaughtered pigs and cattle
II.	Animal insulin is difficult to obtain
III.	Animal insulin is identical to human insulin
IV.	Non-human insulin caused some patients to develop allergy
V.	Recombinant DNA allowed scientists to insert a human insulin gene into a bacterial expression vector
VI.	Recombinant insulin is actually obtained from E. coli bacterial cell

1. Only I and II

2. Only III and IV

3. Only III

4. Only VI

Which step proved to be the main challenging obstacle in the production of human insulin by genetic engineering? 

(1) Splitting A and B polypeptide chains

(2) Addition of C-peptide to pro-insulin

(3) Getting insulin assembled into mature form

(4) Removal of C-peptide from active insulin

Which technique would you expect to be completely curative in SCID?

(1) Gene therapy in adult stage

(2) Gene therapy in embryonic stage

(3) Bone marrow transplantation

(4) Enzyme replacement therapy

For effective treatment of a disease: 

(1) Early diagnosis is needed but understanding of its pathophysiology is not needed

(2) Early diagnosis is not needed but understanding of its pathophysiology is needed

(3) Early diagnosis and understanding of its pathophysiology are needed

(4) Neither early diagnosis nor understanding of its pathophysiology is needed

"Rosie" a transgenic cow known to produce a type of milk which has all the following characteristics except: 

(1) Protein content of 2.4 gm/litre

(2) Has human α-lactalbumin

(3) More balance diet than normal milk for babies

(4) None of these

Which of the following is correct?

(1) The procedure for chemical safety testing / toxicity is the same as that used for testing toxicity of drugs

(2) Transgenic animals are more sensitive to the toxic substances than non-transgenic animals

(3)  Golden rice, a genetically engineered rice has high vitamin A (β-carotene) content

(4) All are correct

Introduction of genetically modified food is not desirable because: 

(1) Allergies and toxicity may be caused

(2) Incorporation of antibiotic resistance in human beings

(3) Disturbance in metabolism due to enzyme for antibiotic resistance 

(4) All are correct

The use of bioresources by multinational companies and other organizations without proper authorization from the countries and people concerned without compensatory payment is called:

(1) Bioethics

(2) Biopiracy

(3) Bioterror

(4) Bioweapon

Which of the following is / are product(s) of genetic engineering:

A. Humulin

B. Hepatitis B vaccine prepared by yeast

C. Golden rice

D. Bt cotton

(1) A, B

(2) B, C

(3) A, B, C

(4) A, B, C, D

Which is incorrect? 

(1) Specific Bt toxin genes have been isolated from Bacillus thuringiensis. 

(3) In mammals insulin is synthesized as a prohormone

(4) ADA deficiency can be cured by bone marrow transplantation