A single gene is usually seen to exhibit a single phenotypic expression. Pleiotropic genes. however, can impact multiple phenotypic expressions. 
Which of these genetic disorders have multiple phenotypic expressions being impacted by a change in a single gene?
1. Thalassemia 
2. Haemophilia
3. Phenylketonuria 
4. Down's syndrome 

Subtopic:  Polygenic Inheritance & Pleiotropy |
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If dark skin colour is controlled by the dominant gene MNO and its recessive allele is mno, what can be DEFINITELY said about the offspring that are dark-skinned?
1. They all have two copies of the dominant alleles.
2. They have at least one copy of the dominant allele.
3. They all have very high exposure to sunlight.
4. They do not have any exposure to sunlight.
Subtopic:  Polygenic Inheritance & Pleiotropy |
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The following statements were noted by a student of grade 12 after studying about Morgan's dihybrid cross experiments with Drosophila. 
1. Two genes chosen in a dihybrid cross are always located on the same chromosome.
2. Genes on the same chromosome are often linked.
3. Linked genes segregate independently during gamete formation.
4. Linked genes do not always obey the law of independent assortment. 
Which of these statement(s) is/are TRUE?
1. only 1
2. only 1 and 2
3. only 2 and 4
4. all- 1, 2, 3, and 4 
Subtopic:  Understanding Linkage |
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The correct statement with respect to Thalassemia in human is:
1. Alpha-thalassemia is controlled by a single gene. 
2. The gene for alpha-thalassemia is located on chromosome-16.
3. Beta-thalassemia is controlled by two closely linked genes HBA-1 and HBA-2.
4. In beta-thalassemia the production of alpha globin chain is affected. 
Subtopic:  Mendelian Disorders: Thalassemia |
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The first scientists to isolate DNA in pure form were:
1. Avery, MacLeod and McCarty
2. Hershey and Chase
3. Nirenberg and Meithei
4. Cohen and Boyer
Subtopic:  Chromosomal Basis of Inheritance: Introduction |
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Genetics deals with:
I: the process by which characters are passed on from parent to progeny.
II: the degree by which progeny differ from their parents.
1. Only I
2. Only II
3. Both I and II
4. Neither I nor II
Subtopic:  Introduction to Genetics: 1 |
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During Mendel’s investigations into inheritance patterns, it was for the first time that:
I: artificial hybridisation experiments were carried out.
II: statistical analysis and mathematical logic were applied to problems in biology.
1. Only I
2. Only II
3. Both I and II
4. Neither I nor II
Subtopic:  Chromosomal Basis of Inheritance: Introduction |
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What would be the number of types of gametes produced by a plant with genotype AaBbCc [assume independent assortment between all loci]?
1. 6
2. 8
3. 9
4. 16
Subtopic:  Dihybrid Cross Analysis |
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In a typical dihybrid cross \(A a B b \times A a B b\) [symbols have usual meanings; assume independent assortment], what proportion of progeny are expected to carry both dominant alleles?
1. ¼
2. 9/16
3. 3/16
4. ½
Subtopic:  Dihybrid Cross Analysis |
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Consider the given two statements:
Statement I: Genes are the units of inheritance and contain the information that is required
to express a particular trait in an organism.
Statement II: Genes which code for a pair of contrasting traits are known as alleles, i.e.,
they are slightly different forms of the same gene
 
1. Statement I is correct; Statement II is incorrect
2. Statement I is correct; Statement II is correct
3. Statement I is incorrect; Statement II is correct
4. Statement I is incorrect; Statement II is incorrect
Subtopic:  Monohybrid Cross: Further Understanding |
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