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Q. No.In the given diagram:
I:
A is 3’-5’ direction.
II:
B is hydrogen bond.
III:
C is phosphodiester bond.
1. Only I and II are correct
2. Only II and III are correct
3. I, II and III are correct
4. I, II, and III are incorrect
Subtopic: DNA Double Helix |
66%
Level 2: 60%+
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Deoxythymidine is:
| 1. | a substituted pyrimidine found only in DNA |
| 2. | a nucleoside monophosphate found only in DNA |
| 3. | a nucleoside found in DNA |
| 4. | a nucleotide formed by chemical modifications in a RNA nucleotide |
Subtopic: DNA Double Helix |
52%
Level 3: 35%-60%
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When compared to DNA, in RNA:
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
| I: | every nucleotide residue has an additional –OH group present at 3'-position in the ribose. |
| II: | 5-methyl uracil is found instead of thymine. |
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic: DNA vs RNA as Genetic Material |
51%
Level 3: 35%-60%
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In 1953, James Watson and Francis Crick, proposed a very simple but famous Double Helix model for the structure of DNA, based on the X-ray diffraction data produced by:
| 1. | Maurice Wilkins and Rosalind Franklin |
| 2. | Beadle and Tatum |
| 3. | Temin and Baltimore |
| 4. | Avery–MacLeod–McCarty |
Subtopic: DNA Double Helix |
95%
Level 1: 80%+
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“For a double stranded DNA, the ratios between Adenine and Thymine and Guanine and Cytosine are constant and equals one” – this statement is known as:
1. Central dogma of molecular biology
2. Chargaff’s rule
3. Tetra-nucelotide hypothesis by Levene
4. Genetic equilibrium
1. Central dogma of molecular biology
2. Chargaff’s rule
3. Tetra-nucelotide hypothesis by Levene
4. Genetic equilibrium
Subtopic: DNA Double Helix |
95%
Level 1: 80%+
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Consider the given two statements:
| Assertion (A): | If the sequence of bases in one strand of the dsDNA molecule is known then the sequence in other strand can be predicted. |
| Reason (R): | The base pairing in a dsDNA molecule is complementary to each other. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Double Helix |
86%
Level 1: 80%+
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How many of the given features will be true for the double-helix structure of DNA?
1. 1
2. 2
3. 3
4. 4
| I: | It is made of two polynucleotide chains |
| II: | The backbone is constituted by sugar-phosphate |
| III: | The two chains have anti-parallel polarity. |
| IV: | The bases in two strands are paired through hydrogen bonds (H-bonds), forming base pairs (bp) |
2. 2
3. 3
4. 4
Subtopic: DNA Double Helix |
92%
Level 1: 80%+
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A hypothetical dsDNA of 100 bp length molecule was found to be composed of 40 Adenine residues. The total number of hydrogen bonds in all base pairs of this molecule is expected to be:
| 1. | 100 | 2. | 130 |
| 3. | 260 | 4. | 300 |
Subtopic: DNA Double Helix |
78%
Level 2: 60%+
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Consider the given two statements:
| Assertion (A): | The distance between a bp in a B-DNA helix is approximately 0.34 nm. |
| Reason (R): | The pitch of the B-DNA helix is 3.4 nm and there are roughly 10 bp in each turn. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Double Helix |
62%
Level 2: 60%+
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Consider the given two statements:
| Assertion (A): | Retroviruses are one known exception to the central dogma in molecular biology as proposed by Francis Crick. |
| Reason (R): | In retroviruses a sequence of nucleotides is copied from an RNA template during the synthesis of a molecule of DNA. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: The DNA |
72%
Level 2: 60%+
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