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Q. No.The methodology used in human genome sequencing that took the blind approach of simply sequencing the
whole set of genome that contained all the coding and non-coding sequence, and later assigning different
regions in the sequence with functions, is called as:
1. Expressed sequence tag
2. Sequence annotation
3. Chain termination
4. Physical mapping
Subtopic: Human Genome Project |
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From NCERT
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The last of the 24 human chromosomes – 22 autosomes and X and Y – to be sequenced was:
1. Chromosome 1
2. the X chromosome
3. the Y chromosome
4. Chromosome 22
1. Chromosome 1
2. the X chromosome
3. the Y chromosome
4. Chromosome 22
Subtopic: Human Genome Project |
88%
From NCERT
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Salient observations drawn from the human genome project include all of the following, except:
| 1. | The human genome contains 3164.7 million bp. |
| 2. | The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. |
| 3. | The total number of genes is estimated at 80,000 to 1,40,000 genes. |
| 4. | Almost all (99.9 per cent) nucleotide bases are exactly the same in all people. |
Subtopic: Human Genome Project |
77%
From NCERT
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In how many base sequences would there be differences in human genome?
1. \(3 \times 10^3~ \mathrm{bp} \)
2. \(3 \times 10^6~ \mathrm{bp} \)
3. \(3 \times 10^9 ~\mathrm{bp} \)
4. \(3 \times 10^{12} ~\mathrm{bp}\)
1. \(3 \times 10^3~ \mathrm{bp} \)
2. \(3 \times 10^6~ \mathrm{bp} \)
3. \(3 \times 10^9 ~\mathrm{bp} \)
4. \(3 \times 10^{12} ~\mathrm{bp}\)
Subtopic: Human Genome Project |
52%
From NCERT
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DNA fingerprinting involves identifying differences in some specific regions in DNA sequence called as:
1. repetitive DNA
2. satellite DNA
3. genomic DNA
4. complementary DNA
1. repetitive DNA
2. satellite DNA
3. genomic DNA
4. complementary DNA
Subtopic: DNA Fingerprinting |
64%
From NCERT
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Consider the given two statements:
| Assertion (A): | DNA fingerprinting is the basis of paternity testing, in case of disputes. |
| Reason (R): | DNA from every tissue (such as blood, hair-follicle, skin, bone, saliva, sperm etc.), from an individual show the same degree of polymorphism. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Fingerprinting |
55%
From NCERT
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Polymorphism in DNA sequence is the basis of:
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
| I: | genetic mapping of human genome |
| II: | DNA fingerprinting |
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic: DNA Fingerprinting |
87%
From NCERT
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Consider the given two statements:
| Assertion (A): | The probability of variation [due to mutation] to be observed in non-coding DNA sequence would be higher than in coding DNA sequence. |
| Reason (R): | Mutations in non-coding DNA sequences may not have any immediate effect/impact in an individual’s reproductive ability. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Fingerprinting |
56%
From NCERT
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The transfer of electrophoresis-separated DNA fragments to a filter membrane in a process called blotting, and the subsequent fragment detection by probe hybridization is called as:
1. Northern Blot
2. Southern Blot
3. Western Blot
4. Eastern Blot
1. Northern Blot
2. Southern Blot
3. Western Blot
4. Eastern Blot
Subtopic: DNA Fingerprinting |
90%
From NCERT
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Consider the given two statements:
| Assertion (A): | Today, DNA from a single cell is enough to perform DNA fingerprinting analysis. |
| Reason (R): | The sensitivity of the technique has been increased by the use of polymerase chain reaction. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Fingerprinting |
72%
From NCERT
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