Q. No.Which kind of therapy was given in 1990 to a four-year-old girl with adenosine deaminase (ADA) deficiency?
1. Radiation therapy
2. Gene therapy
3. Chemotherapy
4. Immunotherapy
1. Radiation therapy
2. Gene therapy
3. Chemotherapy
4. Immunotherapy
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The process of separation and purification of expressed protein before marketing is called:
1. Upstream processing
2. Downstream processing
3. Bioprocessing
4. Postproduction processing
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The DNA fragments separated on an agarose gel can be visualised after staining with
1. Bromophenol blue
2. Acetocarmine
3. Aniline blue
4. Ethidium bromide
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Why does Bt toxin not kill Bacillus thuringiensis?
| 1. | The bacillus keeps proteins in inclusions |
| 2. | The toxin exists in the bacillus as a pro-toxin |
| 3. | The bacillus protects its genetic material by methylation |
| 4. | The bacillus has a tough cell wall of peptidoglycan |
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1. cryIAc
2. cryIIAb
3. cryIAb
4. cryIAd
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RNAi, as a mechanism of cellular defense, takes place in:
| 1. | All bacteria | 2. | All unicellular organisms |
| 3. | All plants only | 4. | All eukaryotic organisms |
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How were nematode-specific genes introduced in tobacco plants?
1. Using page DNA
2. Using a retrovirus
3. By gene gun
4. Using Agrobacterium tumefaciens
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The first recombinant therapeutic product approved for human use was:
| 1. | Humulin | 2. | hGH |
| 3. | Factor VIII clotting factor | 4. | Erythropoietin |
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The first clinical gene therapy trial was given in 1990 to a 4 year girl with:
| 1. | Alpha – 1 antitrypsin deficiency |
| 2. | Cystic fibrosis |
| 3. | Adenosine deaminase deficiency |
| 4. | Chronic myeloid leukemia |
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ELISA is based on the principle of:
1. Antibody opsonization
2. Antigen-antibody interaction
3. Radioactive immune assay
4. Creation of recombinant DNA
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