What radioactive isotope was used in Meselson and Stahl experiment to prove the semi-conservative mode of DNA replication?
1. 35S 2. 32P
3. 15N 4. None

Subtopic:  Search for Genetic Material |
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Under conditions where methionine must be the first amino acid, what protein would be coded for by the following mRNA?

5'-CCUCAUAUGCGCCAUUAUAAGUGACACACA-3'

1. pro his met arg his tyrlyscys his thr
2. met arg his tyrlyscys his thr
3. met arg his tyrlys
4. met pro his met arg his tyrlyscys his thr
Subtopic:  Translation |
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Which of the following is likely if there is a mutation in the lacY gene of the lac operon in E.coli?

1. The lac genes would be expressed efficiently only in the absence of lactose.
2. The lac genes would be expressed efficiently until the lactose supply in the cell is exhausted.
3. The lac genes would be expressed continuously.
4. Expression of the lac genes would cease immediately.

Subtopic:  Gene Regulation: Introduction |
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The difference between ATP and the nucleoside triphosphates used during DNA synthesis is that:

1. The nucleoside triphosphates have the sugar deoxyribose; ATP has the sugar ribose.
2. The nucleoside triphosphates have two phosphate groups; ATP has three phosphate groups.
3. ATP contains three high-energy bonds; the nucleoside triphosphates have two.
4. ATP is found only in human cells; the nucleoside triphosphates are found in all animal and plant cells.
Subtopic:  The DNA |
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Which of the following pairs of codons encode the same amino acid?

1.AUG and AUC2.UAA and UAC
3.GUA and GUG4.UAG and UAC

Subtopic:  Translation |
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The salient features of the human genome include all except:
1. About 1.4 million SNP locations
2. Functions known for less than 50% of the discovered genes
3. The actual number of genes and the initial estimates are remarkable similar
4. More than 98% of genome does not code for proteins

Subtopic:  Human Genome Project |
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In some viruses, DNA is synthesised by using RNA as a template. Such a DNA is called:

1. A-DNA 2. B-DNA
3. cDNA 4. rDNA

Subtopic:  Transcription: IV |
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If Meselson and Stahl's experiment is continued for four generations in bacteria, the ratio of N15/N15: N15/N14: N14/N14 containing DNA in the fourth generation would be:

1. 1:1:0 2. 1:4:0
3. 0:1:3 4. 0:1:7

Subtopic:  Search for Genetic Material:I | Search for Genetic Material: II |
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If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is:

5' -ATGAATG-3',

the sequence of bases in its RNA transcript would be;

1. 5'-AUGAAUG-3'

2. 5'-UACUUAC-3'

3. 5'-CAUUCAU-3'

4. 5'-GUAAGUA-3'

Subtopic:  Transcription: I | Transcription:II |
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The RNA polymerase holoenzyme transcribes:

1. the promoter, structural gene and the terminator region

2. the promoter and the terminator region

3. the structural gene and the terminator region

4. the structural gene only.

Subtopic:  Transcription: III |
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