Q. No.The biochemical evidence for the fact that genetic code is a triplet code and read in a contiguous manner is:
1.
Insertions or deletions caused significant defects in the protein structure.
2.
The effect of single insertions could be remedied by single deletions nearby.
3.
Two nearby insertions caused significant defects in protein structure.
4.
Three insertions near each other often led to minor defects in protein structure.
All the following statements regarding a nucleosome are incorrect except:
1. It contains a single large protein which is connected to DNA by smaller linker proteins.
2. It contains approximately 200 base pairs of DNA.
3. It includes histone and nonhistone proteins.
4. It is a 30 nm diameter structure.
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The spliceosome is composed of :
1. RNA and DNA.
2. Protein and DNA.
3. RNA and protein.
4. Lipids and monosaccharides
What must be true for a transfer RNA molecule?
| 1. | It must have a base pair sequence identical to the codon in the mRNA. |
| 2. | It must be attached to a particular amino acid. |
| 3. | It must bind to the protein to determine the primary sequence. |
| 4. | It must be destroyed immediately after it brings an amino acid to the ribosome. |
The first formed primary structure of a protein molecule represents:
1. Folding of protein due to hydrophobic interactions.
2. Local folding which is stabilized by hydrogen bonds.
3. The sequence of amino acids in the polypeptide.
4. Interactions between two or more polypeptides.
All statements regarding the genetic code is universal except:
1. Most amino acids are specified by more than one codon.
2. Many codons have more than one function.
3. Some organisms use codons differently than other organisms.
4. In some cases, the third base of a codon is nonessential.
Identify the correct statements regarding the structural genes that are part of an operon:
| I: | Tend to be regulated by a common regulatory mechanism. |
| II: | Are generally involved in the same biochemical pathway. |
| III: | Are expressed as a polycistronic RNA. |
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II and III |
All the following are required for accurate transcription except:
1. Regulatory information within the DNA.
2. Proteins which bind to the DNA.
3. Proteins that copy the information from the DNA.
4. Ori.
Select the correct ascending order of the levels of packaging of DNA?
1. Nucleosomes, 30 nm fibers, radial loop domains.
2. 30 nm fibers, nucleosomes, radial loop domains.
3. Nucleosomes, radial loop domains, 30 nm fibers.
4. Radial loop domains, nucleosomes, 30 nm fibers.
Eukaryotic ribosomes [apart from those present in mitochondria and chloroplast] are different from prokaryotic ribosomes. The essential difference will be:
| 1. | Prokaryotic ribosomes consist of two subunits. |
| 2. | Eukaryotic ribosomes consist of both protein and RNA. |
| 3. | Eukaryotic ribosomes are smaller than prokaryotic ribosomes. |
| 4. | None of these. |
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