Q. No.What must be true for a transfer RNA molecule?
1.
It must have a base pair sequence identical to the codon in the mRNA.
2.
It must be attached to a particular amino acid.
3.
It must bind to the protein to determine the primary sequence.
4.
It must be destroyed immediately after it brings an amino acid to the ribosome.
The first formed primary structure of a protein molecule represents:
1. Folding of protein due to hydrophobic interactions.
2. Local folding which is stabilized by hydrogen bonds.
3. The sequence of amino acids in the polypeptide.
4. Interactions between two or more polypeptides.
All statements regarding the genetic code is universal except:
1. Most amino acids are specified by more than one codon.
2. Many codons have more than one function.
3. Some organisms use codons differently than other organisms.
4. In some cases, the third base of a codon is nonessential.
Identify the correct statements regarding the structural genes that are part of an operon:
| I: | Tend to be regulated by a common regulatory mechanism. |
| II: | Are generally involved in the same biochemical pathway. |
| III: | Are expressed as a polycistronic RNA. |
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II and III |
All the following are required for accurate transcription except:
1. Regulatory information within the DNA.
2. Proteins which bind to the DNA.
3. Proteins that copy the information from the DNA.
4. Ori.
Select the correct ascending order of the levels of packaging of DNA?
1. Nucleosomes, 30 nm fibers, radial loop domains.
2. 30 nm fibers, nucleosomes, radial loop domains.
3. Nucleosomes, radial loop domains, 30 nm fibers.
4. Radial loop domains, nucleosomes, 30 nm fibers.
Eukaryotic ribosomes [apart from those present in mitochondria and chloroplast] are different from prokaryotic ribosomes. The essential difference will be:
| 1. | Prokaryotic ribosomes consist of two subunits. |
| 2. | Eukaryotic ribosomes consist of both protein and RNA. |
| 3. | Eukaryotic ribosomes are smaller than prokaryotic ribosomes. |
| 4. | None of these. |
The enzyme aminoacyl-tRNAsynthetase is able to recognize all the following in the tRNA molecule except:
1. The acceptor stem.
2. Bases in the stem loop regions.
3. The anticodon region.
4. 5’ end.
A mutation leading to the formation of a nonfunctional sigma subunit of RNA polymerase holoenzyme in prokaryotes will result in bacteria being unable to:
1. assemble RNA polymerase onto the DNA strand.
2. identify and tightly bind promoter elements.
3. convert a closed complex to an open complex.
4. synthesize RNA once an open complex is formed.
The 5’ cap in the final transcript in eukaryotic mRNA helps in:
1. Protection from inappropriate splicing.
2. Synthesis of the polyA tail.
3. Transport of mRNAs into the nucleus.
4. Recognition of the 5' end of the transcript by a ribosome.
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