A mutation leading to the formation of a nonfunctional sigma subunit of RNA polymerase holoenzyme in prokaryotes will result in bacteria being unable to:
1. assemble RNA polymerase onto the DNA strand.
2. identify and tightly bind promoter elements.
3. convert a closed complex to an open complex.
4. synthesize RNA once an open complex is formed.

Subtopic:  Mutations and Genetic Code |
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The 5’ cap in the final transcript in eukaryotic mRNA helps in:
1. Protection from inappropriate splicing.
2. Synthesis of the polyA tail.
3. Transport of mRNAs into the nucleus.
4. Recognition of the 5' end of the transcript by a ribosome.

Subtopic:  Transcription |
 53%

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What would be the actual inducer for the lac operon?

1.lactose2.allolactose
3.ß-galactosidase4.galactose

Subtopic:  Gene Regulation: Lac Operon |

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3 out of 64 codons are termination codons. These termination codons:
1. recognise a single tRNA
2. are capable of binding to many different tRNAs
3. bind to release factors instead of tRNAs
4. only specify a single amino acid

Subtopic:  Genetic Code: I |
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RNA molecules can have catalytic functions as well. A well known example would be:
1. Polynucleotide kinase.
2. Base pair recognition.
3. Methyl transferase.
4. Peptidyl transferase.

Subtopic:  DNA vs RNA as Genetic Material |
 68%

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Removal of introns describes which of the following processes in relation to the primary transcript in eukaryotes?
1. Trimming
2. 5' capping
3. Poly-A tailing
4. Splicing

Subtopic:  Transcription: I |
 93%
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The primary RNA transcript in eukaryotes contains introns. This can be demonstrated by:

I: A comparison of the DNA and mRNA sequences.
II: A comparison of the genomic DNA and cDNA sequences.
III: A hybridization between DNA and mRNA molecules.
 
1. I and II only 2. I and III only
3. II and III only 4. I, II, and III
Subtopic:  Transcription: I |
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Two amino acids will differ from each other in their properties because they have different:
1. The amino group.
2. The carboxyl group.
3. The R group.
4. Peptide bonds.

Subtopic:  Genetic Code: II |
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Identify the statement that will be incorrect for transcription in both prokaryotes and eukaryotes:

1. RNA polymerase identifies and binds to specific promoter elements in the DNA.
2. Transcription factors control the binding of RNA polymerase.
3. RNA polymerase opens a double-stranded DNA to expose the template strand.
4. RNA polymerase catalyzes RNA synthesis from 3' to 5' of the new strand.
Subtopic:  Transcription |
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Oculocutaneous albinism is a genetic disorder in human characterized by lack of pigmentation of skin. This can be caused by all the following except:
1. Lack of an enzyme that synthesizes the pigment molecules.
2. Lack of a protein that transports the pigment molecules to the appropriate location.
3. Lack of a receptor protein that allows the pigment to be taken up into appropriate cells.
4. Exposer to colder environment for a long period

Subtopic:  Genetic Code: I |
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