Q. No.RNA molecules can have catalytic functions as well. A well known example would be:
1. Polynucleotide kinase.
2. Base pair recognition.
3. Methyl transferase.
4. Peptidyl transferase.
1. Polynucleotide kinase.
2. Base pair recognition.
3. Methyl transferase.
4. Peptidyl transferase.
Removal of introns describes which of the following processes in relation to the primary transcript in eukaryotes?
1. Trimming
2. 5' capping
3. Poly-A tailing
4. Splicing
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The primary RNA transcript in eukaryotes contains introns. This can be demonstrated by:
| I: | A comparison of the DNA and mRNA sequences. |
| II: | A comparison of the genomic DNA and cDNA sequences. |
| III: | A hybridization between DNA and mRNA molecules. |
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
Two amino acids will differ from each other in their properties because they have different:
1. The amino group.
2. The carboxyl group.
3. The R group.
4. Peptide bonds.
Identify the statement that will be incorrect for transcription in both prokaryotes and eukaryotes:
| 1. | RNA polymerase identifies and binds to specific promoter elements in the DNA. |
| 2. | Transcription factors control the binding of RNA polymerase. |
| 3. | RNA polymerase opens a double-stranded DNA to expose the template strand. |
| 4. | RNA polymerase catalyzes RNA synthesis from 3' to 5' of the new strand. |
Oculocutaneous albinism is a genetic disorder in human characterized by lack of pigmentation of skin. This can be caused by all the following except:
1. Lack of an enzyme that synthesizes the pigment molecules.
2. Lack of a protein that transports the pigment molecules to the appropriate location.
3. Lack of a receptor protein that allows the pigment to be taken up into appropriate cells.
4. Exposer to colder environment for a long period
The use of proflavin in his experiments enabled Francis Crick to determine that the genetic code is a triplet code because:
1. It causes mutations in DNA.
2. It can cause large deletions in DNA.
3. It causes single insertions or deletions in DNA sequences.
4. It can be lethal.
What would be true for the mutation that leads to sickle cell anemia ?
| I: | Is a base substitution. |
| II: | Is a deleterious mutation. |
| III: | Is a missense mutation. |
| 1. | I and II only | 2. | I and III only |
| 3. | II and III only | 4. | I, II, and III |
All the following regarding RNA splicing are correct except:
1. Some introns can splice themselves out.
2. Splicing is required for some tRNAs.
3. The final step of splicing is formation of a phosphodiester linkage.
4. Introns often have a specific function after they are removed.
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The essential difference between DNA replication in eukaryotes and prokaryotes will be:
1. A high % of AT base pairs in Ori region of eukryotic DNA.
2. Bidirectional movement of replication fork in eukaryotes.
3. Eukaryotes contain several different DNA polymerases.
4. Telomerase required to replicate the ends of eukaryotic chromosomes.
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