Antisense RNA is:
(1) RNA that makes opposite sense
(2) RNA that investigators find confusing
(3) The non-coding strand of DNA molecule
(4) RNA that is complementary to certain mRNA
Which of the following statements is false?
I. | Insulin was originally extracted from pancreas of slaughtered pigs and cattle |
II. | Animal insulin is difficult to obtain |
III. | Animal insulin is identical to human insulin |
IV. | Non-human insulin caused some patients to develop allergy |
V. | Recombinant DNA allowed scientists to insert a human insulin gene into a bacterial expression vector |
VI. | Recombinant insulin is actually obtained from E. coli bacterial cell |
1. Only I and II
2. Only III and IV
3. Only III
4. Only VI
Which step proved to be the main challenging obstacle in the production of human insulin by genetic engineering?
(1) Splitting A and B polypeptide chains
(2) Addition of C-peptide to pro-insulin
(3) Getting insulin assembled into mature form
(4) Removal of C-peptide from active insulin
Which technique would you expect to be completely curative in SCID?
(1) Gene therapy in adult stage
(2) Gene therapy in embryonic stage
(3) Bone marrow transplantation
(4) Enzyme replacement therapy
For effective treatment of a disease:
(1) Early diagnosis is needed but understanding of its pathophysiology is not needed
(2) Early diagnosis is not needed but understanding of its pathophysiology is needed
(3) Early diagnosis and understanding of its pathophysiology are needed
(4) Neither early diagnosis nor understanding of its pathophysiology is needed
"Rosie" a transgenic cow known to produce a type of milk which has all the following characteristics except:
(1) Protein content of 2.4 gm/litre
(2) Has human α-lactalbumin
(3) More balance diet than normal milk for babies
(4) None of these
Which of the following is correct?
(1) The procedure for chemical safety testing / toxicity is the same as that used for testing toxicity of drugs
(2) Transgenic animals are more sensitive to the toxic substances than non-transgenic animals
(3) Golden rice, a genetically engineered rice has high vitamin A (β-carotene) content
(4) All are correct
Introduction of genetically modified food is not desirable because:
(1) Allergies and toxicity may be caused
(2) Incorporation of antibiotic resistance in human beings
(3) Disturbance in metabolism due to enzyme for antibiotic resistance
(4) All are correct
The use of bioresources by multinational companies and other organizations without proper authorization from the countries and people concerned without compensatory payment is called:
(1) Bioethics
(2) Biopiracy
(3) Bioterror
(4) Bioweapon
Which of the following statement is not true:
(1) Transformation is a procedure through which a piece of DNA is introduced in a host bacterium
(2) Normally, the genes encoding resistance to antibiotics are considered useful selectable markers for E.coli
(3) The normal E.coli cells do not carry resistance against antibiotics such as ampicillin, chloramphenicol, tetracycline or kanamycin
(4) Presence of one recognition sites within the vector will generate several fragments, which will complicate the gene cloning