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Q. No.The important goals of HGP included all of the following, except:
1.
Identify all the approximately 20,000–25,000 genes in human DNA
2.
Determine the sequences of the 3 billion chemical base pairs that make up human DNA
3.
Develop technology for cloning of human beings
4.
Address the ethical, legal, and social issues (ELSI) that may arise from the project.
Subtopic: Human Genome Project |
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Many non-human model organisms have also been sequenced even before sequencing of human genome where:
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
| I: | Caenorhabditis elegans is a pathogenic nematode |
| II: | Arabidopsis thaliana is a fungus |
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic: Human Genome Project |
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The methodology used in human genome sequencing that took the blind approach of simply sequencing the
whole set of genome that contained all the coding and non-coding sequence, and later assigning different
regions in the sequence with functions, is called as:
1. Expressed sequence tag
2. Sequence annotation
3. Chain termination
4. Physical mapping
whole set of genome that contained all the coding and non-coding sequence, and later assigning different
regions in the sequence with functions, is called as:
1. Expressed sequence tag
2. Sequence annotation
3. Chain termination
4. Physical mapping
Subtopic: Human Genome Project |
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From NCERT
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The last of the 24 human chromosomes – 22 autosomes and X and Y – to be sequenced was:
1. Chromosome 1
2. the X chromosome
3. the Y chromosome
4. Chromosome 22
1. Chromosome 1
2. the X chromosome
3. the Y chromosome
4. Chromosome 22
Subtopic: Human Genome Project |
88%
From NCERT
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Salient observations drawn from the human genome project include all of the following, except:
| 1. | The human genome contains 3164.7 million bp. |
| 2. | The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. |
| 3. | The total number of genes is estimated at 80,000 to 1,40,000 genes. |
| 4. | Almost all (99.9 per cent) nucleotide bases are exactly the same in all people. |
Subtopic: Human Genome Project |
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In how many base sequences would there be differences in human genome?
1. \(3 \times 10^3~ \mathrm{bp} \)
2. \(3 \times 10^6~ \mathrm{bp} \)
3. \(3 \times 10^9 ~\mathrm{bp} \)
4. \(3 \times 10^{12} ~\mathrm{bp}\)
1. \(3 \times 10^3~ \mathrm{bp} \)
2. \(3 \times 10^6~ \mathrm{bp} \)
3. \(3 \times 10^9 ~\mathrm{bp} \)
4. \(3 \times 10^{12} ~\mathrm{bp}\)
Subtopic: Human Genome Project |
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From NCERT
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DNA fingerprinting involves identifying differences in some specific regions in DNA sequence called as:
1. repetitive DNA
2. satellite DNA
3. genomic DNA
4. complementary DNA
1. repetitive DNA
2. satellite DNA
3. genomic DNA
4. complementary DNA
Subtopic: DNA Fingerprinting |
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From NCERT
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Consider the given two statements:
| Assertion (A): | DNA fingerprinting is the basis of paternity testing, in case of disputes. |
| Reason (R): | DNA from every tissue (such as blood, hair-follicle, skin, bone, saliva, sperm etc.), from an individual show the same degree of polymorphism. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Fingerprinting |
55%
From NCERT
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Polymorphism in DNA sequence is the basis of:
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
| I: | genetic mapping of human genome |
| II: | DNA fingerprinting |
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic: DNA Fingerprinting |
87%
From NCERT
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Consider the given two statements:
| Assertion (A): | The probability of variation [due to mutation] to be observed in non-coding DNA sequence would be higher than in coding DNA sequence. |
| Reason (R): | Mutations in non-coding DNA sequences may not have any immediate effect/impact in an individual’s reproductive ability. |
| 1. | Both (A) and (R) are True but (R) does not correctly explain (A). |
| 2. | (A) is True but (R) is False. |
| 3. | (A) is False but (R) is True. |
| 4. | Both (A) and (R) are True and (R) correctly explains (A). |
Subtopic: DNA Fingerprinting |
56%
From NCERT
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