Matthew Meselson and Franklin Stahl , in1958, demonstrated that DNA replication produces two daughter DNA molecules each composed of:
1. two old strands
2. two new strands
3. one old and one new strand
4. two strands with variable proportion of new and old DNA

Subtopic:  Search for Genetic Material: II |
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Consider the given two statements:
Assertion: On one strand (the template with polarity 3'→5'), the replication is continuous, while on the other (the template with polarity 5'→3'), it is discontinuous.
Reason: The DNA-dependent DNA polymerases catalyse polymerisation only in one direction, that is 3'→5'.
 
1. Both Assertion and Reason are true but Reason does not correctly explain the Assertion.
2. Assertion is true but Reason is False.
3. Assertion is false but Reason is True.
4. Both Assertion and Reason are true and Reason correctly explains the Assertion.
Subtopic:  DNA Replication: II |
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While defining the two strands of the DNA in the structural gene of a transcription unit the coding strand is the one that:
1. has the polarity 3'→5'
2. has the sequence same as RNA (except uracil at the place of thymine)
3. is displaced during transcription
4. codes for the transcript formed
Subtopic:  Transcription:II |
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Consider the given two statements:
Statement I: The structural gene in a transcription unit is monocistronic, mostly, in bacteria or prokaryotes.
Statement II: The structural gene in a transcription unit is polycistronic, mostly, in eukaryotes.
 
1. Statement I is correct; Statement II is correct
2. Statement I is correct; Statement II is incorrect
3. Statement I is incorrect; Statement II is incorrect
4. Statement I is incorrect; Statement II is correct
Subtopic:  Transcription:II |
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Regarding bacterial RNA polymerase:
I: There is a single DNA-dependent RNA polymerase that catalyzes the transcription of all types of RNA.
II: RNA polymerase associates transiently with initiation-factor (σ) and termination-factor (ρ) to initiate and terminate the transcription, respectively.
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic:  Transcription:II |
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In eukaryotic transcription:
I: There are at least three RNA polymerases in the nucleus (in addition to the RNA polymerase found in the organelles).
II: hnRNA undergoes modification to produce mature RNA.
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic:  Transcription:II |
 90%
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How many of the following statements regarding the salient features of genetic code are true?
I: The codon is triplet.
II: 61 codons code for amino acids and 3 codons do not code for any amino acids.
III: The code is degenerate.
IV: There are punctuations when reading the code.
V: The code is nearly universal.
VI: AUG has dual functions.
1. 3
2. 4
3. 5
4. 6
Subtopic:  Genetic Code: II |
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Identify the correct statements regarding the tRNA molecule:
a. tRNA has an anticodon loop that has bases complementary to the code.
b. tRNA has an amino acid acceptor end at the 5’ end to which it binds to amino acids.
c. tRNAs are specific for each amino acid.
d. There are no tRNAs for stop codons.
1. Only a, b and c
2. Only a, c and d
3. Only b, c and d
4. a, b, c, and d
Subtopic:  Transcription:II |
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The clover leaf model structure describes the:
1. the secondary structure of tRNA.
2. the actual structure of tRNA.
3. the assembly of tRNAs at the larger subunit of ribosomes
4. motifs formed by unusual bases in tRNA.
Subtopic:  Translation Mechanism |
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The UTRs in a mature eukaryotic mRNA:
 
1. are present at both 5'-end (before start codon) and at 3'-end (after stop codon).
2. are present only at 5'-end (before start codon).
3. are present only at 3'-end (after stop codon).
4. are absent but are present in hnRNA.
Subtopic:  Transcription: IV |
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