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Q. No.Identify the correct statements regarding the tRNA molecule:
a.
tRNA has an anticodon loop that has bases complementary to the code.
b.
tRNA has an amino acid acceptor end at the 5’ end to which it binds to amino acids.
c.
tRNAs are specific for each amino acid.
d.
There are no tRNAs for stop codons.
1. Only a, b and c
2. Only a, c and d
3. Only b, c and d
4. a, b, c, and d
Subtopic: Transcription:II |
61%
Level 2: 60%+
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The clover leaf model structure describes the:
| 1. | the secondary structure of tRNA. |
| 2. | the actual structure of tRNA. |
| 3. | the assembly of tRNAs at the larger subunit of ribosomes |
| 4. | motifs formed by unusual bases in tRNA. |
Subtopic: Translation Mechanism |
79%
Level 2: 60%+
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The UTRs in a mature eukaryotic mRNA:
| 1. | are present at both 5'-end (before start codon) and at 3'-end (after stop codon). |
| 2. | are present only at 5'-end (before start codon). |
| 3. | are present only at 3'-end (after stop codon). |
| 4. | are absent but are present in hnRNA. |
Subtopic: Transcription: IV |
91%
Level 1: 80%+
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Consider the given two statements:
1. Both I and II are correct
2. Only II is correct
3. Only I is correct
4. Both I and II are incorrect
| Statement I: | A transcription unit in DNA is the structural gene that is flanked by the promoter and the terminator. |
| Statement II: | A translational unit in mRNA is the sequence of RNA that is flanked by the start codon (AUG) and the stop codon |
1. Both I and II are correct
2. Only II is correct
3. Only I is correct
4. Both I and II are incorrect
Subtopic: Transcription:II |
85%
Level 1: 80%+
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Among the given possible levels of regulation of gene expression:
(i) transcriptional level (formation of primary transcript),
(ii) processing level (regulation of splicing),
(iii) transport of mRNA from nucleus to the cytoplasm,
I: (i) is the predominant site for regulation of gene expression in prokaryotes.
II: (ii) and (iii) are possible only in eukaryotes.
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
(i) transcriptional level (formation of primary transcript),
(ii) processing level (regulation of splicing),
(iii) transport of mRNA from nucleus to the cytoplasm,
I: (i) is the predominant site for regulation of gene expression in prokaryotes.
II: (ii) and (iii) are possible only in eukaryotes.
1. Only I is correct
2. Only II is correct
3. Both I and II are correct
4. Both I and II are incorrect
Subtopic: Transcription:II |
84%
Level 1: 80%+
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In a transcription unit, the activity of RNA polymerase at a given promoter is regulated by interaction with accessory proteins called:
1. Enhancers and Silencers
2. Operators and CAP
3. Rho factors and Sigma factors
4. Activators and Repressors
1. Enhancers and Silencers
2. Operators and CAP
3. Rho factors and Sigma factors
4. Activators and Repressors
Subtopic: Transcription:II |
Level 4: Below 35%
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The accessibility of promoter regions of prokaryotic DNA is in many cases regulated by the interaction of
proteins with sequences termed:
1. Enhancers
2. Silencers
3. Operators
4. Terminators
proteins with sequences termed:
1. Enhancers
2. Silencers
3. Operators
4. Terminators
Subtopic: Gene Regulation: Lac Operon |
87%
Level 1: 80%+
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The first to elucidate a transcriptionally regulated system of gene expression were:
1. Jacob and Monod
2. Nirenberg and Khorana
3. Tijo and Levan
4. Beadle and Tatum
1. Jacob and Monod
2. Nirenberg and Khorana
3. Tijo and Levan
4. Beadle and Tatum
Subtopic: Transcription:II |
81%
Level 1: 80%+
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Which of the following statements will be true regarding the effect of mutations in the components of the lac operon of E. coli [assume mutations will lead to loss of function in the affected gene]?
1. Only I and II are correct
2. Only I and III are correct
3. Only II and III are correct
4. I, II and III are correct
| I: | A mutation in the i gene will lead to a stoppage of transcription of the operon. |
| II: | A mutation in the z gene will lead to an inability in E .coli to hydrolyze the disaccharide, lactose. |
| III: | A mutation in the y gene will lead to an inability in E. coli to pick up lactose from its surroundings. |
1. Only I and II are correct
2. Only I and III are correct
3. Only II and III are correct
4. I, II and III are correct
Subtopic: Gene Regulation: Lac Operon |
55%
Level 3: 35%-60%
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Which of the following is synthesised all-the-time – constitutively in E .coli?
1. repressor of the lac operon
2. beta galactosidase
3. permease
4. transacetylase
1. repressor of the lac operon
2. beta galactosidase
3. permease
4. transacetylase
Subtopic: Gene Regulation: Lac Operon |
72%
Level 2: 60%+
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